Indian Journal of Public Health Research & Development

C. Sakphisutthikul ¹, P. Sanchaisuriya ¹

Affiliations
1 Khon Kaen University, Khon Kaen-40002, TH

Abstract

Enteral nutrition is the best way to feed or supplement the diet when gastrointestinal tract functions of patients are partially or totally preserved. Whenever total enteral nutrition is needed, it represents the only source of nutrients for patients. Thus, it is mandatory to ensure that high biological value proteins are included in enteral formula.

Objective:To investigate the nutritional effectiveness of protein blend constituted intended to be used in enteral nutrition products.

Materials and Method:27 male Wistar rats, with initial body weight of 60±5 g, where divided into three groups and feed for 28 days with: Group A were fed ONS-ST, Group B were fed ONS-HP, and Group C were fed ONS-PF. Enteral diet was fed 30 g./day during 4 weeks and consumption was recorded every day. Observation on body weight and food consumption were determined during the Study. Growth study(PER and NPRR) and digestibility study (TD, BV and NPU) where calculated. Results: The obtained results for growth study and digestibility indicated that the supplement prepared with local food was a good protein source, especially when protein-mix was added.Experimental (Group B) and standard(Group A)had similar values for all analysed indices (PER, NPRR, TD, BV and NPU). These indices where also similar Group C, but lower than experimental and standard groups.

Conclusion:The nutritional effectiveness of ONS-HP versus ONS-ST when administered for 4 weeks to rats were compared. There were no differences between the ONS-HP group and ONS-ST group in body weight and nitrogen balance. Additionally, there were no adverse effects associated with administration of ONS-HP. These results suggest that ONS-HP is as nutritionally effective as ONS-ST, and as useful for nutritional management as conventional enteral nutrition formulas, even in a lower administration volume.

Keywords

Nutritional Evaluation, High Protein, Supplement Diet, Biological Assay, Wistar Rat.

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C. Sakphisutthikul ¹, P. Sanchaisuriya ¹

Affiliations
1 Khon Kaen University, Khon Kaen-40002, TH

Abstract

Enteral diet formula has shown to be beneficial in hemodialysis patients, where otherwise the gut is efficacious in digestion and absorption of food but oral intake is not possible due to anorexia, and side effects of treatments. Long term enteral feeding programmed with extreme use of commercially available expensive enteral formula all pose a requirement of development of an low cost diet Formula. The objective of this study was to appraisal of formulation and analyze its nutritional composition in comparison to other commercial formula available in market. Material and Method: The renal specific formula was developed by undergoing to different procedures. Samples of two different enteral formula (one renal specific formula and one commercial) were collected from each hospital on three separate occasions and evaluated for nutritional value and cost. Results: The results were compared with the nutritional requirements proposed by the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative (K/DOQI) and the European Society for Clinical Nutrition and Metabolism (ESPEN) to enteral renal specific formula. This study demonstrates that hospital prepared enteral renal specific formula render unpredictable levels of micronutrients and macronutrients and appear likely to deliver less than the desired amounts of nutrients. The analysis showed diets with a normal distribution of carbohydrates. The total amount of dietary fiber in the renal specific formula was between 12 g and 15 g. In commercial formula dietary fiber was 3.40 g. Concerning minerals, all formulations were appropriate in iron and most of them in calcium, phosphorus, and sodium. No formulation evaluated presented appropriate values of potassium and magnesium. Additionally, the viscosity of renal specific formulas may be unsuitable for infusion through feeding tubes. The cost of the enteral renal specific formulas ranges from 60 – 88 baht/feed Conclusion: Enteral renal specific formula offers an efficacious, nutrient dense alternative, with known specifications, to assist medical professionals optimize nutritional strategies and improve clinical outcomes within the complex etiology in renal disease patient.

Keywords

Formulation, Nutritional Appraisal, Renal, Specific Formula.

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