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Abiodun, Afolabi Emmanuel
- Alterations in some Biochemical Indices of Hepatic Function in Tuberculosis Patients on Antituberclosis Therapy
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Authors
Nnodim Johnkennedy
1,
Afolabi Emmanuel Abiodun
1,
Udujih Hellen Ifeoma
1,
Okorie Hope
1,
Nwobodo Emmanuel Ikechukwu
2,
Nwadike Constance Nnedimma
1
Affiliations
1 Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, NG
2 Thank god medical Laboratories Ihiala, Anambra State, NG
1 Department of medical laboratory science, faculty of health science, Imo State University Owerri, Imo State, NG
2 Thank god medical Laboratories Ihiala, Anambra State, NG
Source
Indian Journal of Medicine and Healthcare, Vol 1, No 1 (2012), Pagination: 12-15Abstract
This study was to investigate the hepatic pathophysiology and biochemical changes during antituberclosis therapy. Among the intake 200 patients: 60 were on therapy, another 60 were not on therapy, while 80 were non tuberculosis patient. A comparative decrease in the level of total protein and albumin in tuberculosis patients were recorded while increase in Asparate Aminotransfarace (AST), Alanine Aminotransferace (ALT), and Alkaline Phosphatase (ALP) were observed in comparison with the control. On treatment with antituberclosis therapy, the hepatic involvements are transient.Keywords
Biochemical Indices, Hepatic Pathophysiology, Antituberculosis TherapyFull Text
References
- Nnodim JK, Anyado SO and NwosuNjoku CE (2011) The antioxidant status and lipid peroxidation product of newly diagnosed and 6 weeks follow-up patients with pulmonary tuberculosis in Owerri, Imo State. Asian Pacific J.Tropical Disease. 1(4), 292- 294.
- Hardy MA and Schumidek HH (1968). Epidemiology of tuberculosis aboad a ship.JAMA . pp: 203-175.
- Cantwell MF, Shehab ZM and Costello AM (1994) Brief reports. Congenital tuberculosis. N. Engl. J. Med.330 (15), 1051-1054.
- Akiibinu MO, Arinola OG and Ogunyemi EO (2009) Plasma neopterin and peroxide levels in pulmonary tuberclosis patients on chemotherapy with or without micronutrient supplementation. Pak. J. Med. Sci. 25 (3), 380-385.
- Hill AR and Premkumar S (1991) Disseminated tuberculosis in the acquired immunodeficiency syndrome era. Am Rev Respir Dis.144,1164 -1170.
- Essop AR, Posen JA and Hodkinson JH (1984) Tuberculosis hepatitis: a clinical review of 96 cases. QJ.Med. 53, 465 – 477.
- Kimmoun E and Samuel D (2002) Antituberculous drugs in patients with chronic liver disease. J.Gastroenterol Hepatol.17:408-412.
- Sasaki Y, Yamagishi F, Yasi T and Mizutani F (1999) A case of pulmonary tuberculosis case with pancytopenia accompanied to bone marrow gelatinous transformation.Kekaku,74 (4),361-364.
- Yamanaka K, Sakai S, Nomura F, Akashi T and Usui T (2001). A nutritional investigation of homeless patients with tuberculosis. Kekkaku.76 (4),363-370.
- Aily DC, Camargo SS and Paro HS (1999).Systemic mycobacterioses in AIDS patients as determined by blood cultures on biphasic medium. Rev Argent Microbiol. 31(2), 53-7.
- Paton NI, Chua YK, Earnest A and Chee CB (2004) Randomized controlled trial of nutritional supplementation in patients with newly diagnosed tuberculosis and wasting. Am. J. Clin. Nutr. 80(2):460-465.
- Pessayre D, Bentata M and Degott C (1977) Isoniazid rifampicin fulminant hepatitis. Gastroenterology.72,284–289.
- Tost JR, Vidal R, Cayla J, Diaz-Cabanela D, Jimenez A and Broquetas JM (2005) Severe hepatoxicity due to anti-tuberculosis drugs in Spain. Int. J. Tuberc. Lung Dis. pp: 534-540.
- Niwa Y, Sakane T, Miyachi Y and Ozaki M (1984) Oxygen metabolism in phagocytes of leprotic patients. enhanced endogenous superoxide dismutase activity and hydroxyl radical generation by clofazimine. J. Clin. Microbiol.20, 837-842.
- Arun Kulkarni and Narayan A. Madrasi (2008). Relationship of nitric oxide and protein carbonyl in tuberculosis. Indian J. Tuberc.55, 138-144.
- Ragunath R Rai and Madhavi S Phadke (2006) Plasma oxidant antioxidant status in different respiratory disorder. Indian J. of Clini. Biochem.21 (2)161-164.
- Sardesai VM (1995) Role of antioxidants in health maintenance. Nutr. Clin .pract. 10(1) 19-25.