Indian Journal of Forensic Medicine & Toxicology

MuathJabbar Tarfa Al-Abbasee ¹, Hamid J. Mohammad ², Mawlood K. Mawlood ¹

Affiliations
1 Chemistry Department, College of Education, University of Samarra, IQ
2 Chemistry Department, College of Applied Sciences, University of Samarra, IQ

Abstract

A simple and efficient one-pot synthesis of bicyclic nitro pyrazolone derivatives in traditional alcoholic solvents under refluxing conditions, The chemical structure of the synthesized derivatives was substantiated byFT-IR,1H NMR ,13C-NMRand CHNS analysis, All of these compounds of the series have been testedin vitro asantibacterial and antifungalagents against four types of organisms. The minimum and maximum inhibitory concentrations were determined against each organism.

Keywords

Pyrazolone, One-Pot Synthesis, Nitroaldehyde, Antibacterial Activity, Antifungi Activity.

Full Text