Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Histopathological Evaluation of Liver Autopsies in a Tertiary Care Hospital: A Case Series


Affiliations
1 Department of Pathology, G.G.S. Medical College & Hospital , Faridkot
2 Department of Pathology, G.G.S. Medical College & Hospital , Faridkot, India
3 C.H.C. Sadiq, Faridkot, India
4 Department of Community Medicine, G.G. S. Medical College & Hospital, Faridkot, India
5 Department of Pathology, G.G. S. Medical College & Hospital, Faridkot, India
     

   Subscribe/Renew Journal


A wide spectrum of Primary as well as secondary diseases can affect liver. With the rare exception of fulminant hepatic failure, liver disease is an insidious process in which clinical detection and symptoms of hepatic decompensation may occur weeks, months or many years after the onset of injury .Liver injury and healing may also occur without even clinical detection. Liver histopathology remains a mainstay in the diagnostic workup of most liver diseases. Liver autopsies are a wonderful learning tool for clinicians as well as pathologists. They help in formulating exact liver disease burden in the population .Present study was conducted between the period of 2008 - 2012 consisting of 154 cases. Fatty change liver (Steatosis) was found to be the most common disease entity followed by hepatitis.

Keywords

Fatty Change (Steatosis), Hepatitis, Cirrhosis
Subscription Login to verify subscription
User
Notifications
Font Size


  • Lim Y S, Kim W R.The global impact of hepatic fibrosis and end stage liver disease Clin Liver Dis, 2008, 12 : 733.
  • Crawford J M, Lin Chen. Liver and biliary tract, 8th Ed., Robbins and Cotran pathologic basis of disease. Saunders company 2010 ; 835.
  • Murphy S. Deaths : Final data for 1998. National vital statistics reports. Hyattsville, MD : National centre for Health Statistics, 2000, Vol. 48.
  • Desmet V.J, Rosai Juan : Liver, 9th Ed. Rosai and Ackerman’s surgical pathology Mosby Company 2009 ; Vol. 1 : 919.
  • Bedongi G, Miglioli L, Masutti F,Tirribelli C, Marchesini G, Bellentani S. Prevalence of and risk factors for non-alcoholic fatty liver disease. Hepatology 2005; 42 : 44 – 52.
  • Kim HJ, Kim HJ, Lee KE, Kim DJ, Kim SK, Ahn CW, et al.Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. Arch Intern Med. 2004 ; 164 : 2169 – 75.
  • Bellantani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, et al. Prevalence of and risk factors for hepatic Steatosis in Northern Italy. Ann Intern Med 2000, 132 : 112 – 117.
  • James O, Day P. Nonalcoholic steatohepatitis (NASH): a disease of emerging identity and importance. J Hepatol 1998; 29 : 495 - 501.
  • Czaja A, Carpenter H, Santroch P, et al. Host and disease specific factors affecting steatosis in chronic hepatitis C.J Hepatol 1998, 29 : 198 – 206.
  • Amarapurkar A, Ghansar T. Fatty liver : Experience from western India. Annals of Hepatology 2007 ; 6 (1) : Jan – Mar : 37 – 40.
  • Bal MS, Singh SP, Bodal VK, Oberoi SS, Surinder K.. Pathologic findings in liver autopsy. JIAFM, 2004 ; 26(2) : 55-57.
  • Caplan Lawrence H., Simon Manfred. Nonparasitic cysts of the liver. Am. Journal of roentgenology 1966 ; Vol. 96, No. 2. : 421-428.

Abstract Views: 448

PDF Views: 0




  • Histopathological Evaluation of Liver Autopsies in a Tertiary Care Hospital: A Case Series

Abstract Views: 448  |  PDF Views: 0

Authors

Sarita Nibhoria
Department of Pathology, G.G.S. Medical College & Hospital , Faridkot
Kanwardeep Kaur Jhajj
Department of Pathology, G.G.S. Medical College & Hospital , Faridkot, India
Varinder Nibhoria
C.H.C. Sadiq, Faridkot, India
Preeti Padda
Department of Community Medicine, G.G. S. Medical College & Hospital, Faridkot, India
Samarjit Kaur Sandhu
Department of Pathology, G.G. S. Medical College & Hospital, Faridkot, India

Abstract


A wide spectrum of Primary as well as secondary diseases can affect liver. With the rare exception of fulminant hepatic failure, liver disease is an insidious process in which clinical detection and symptoms of hepatic decompensation may occur weeks, months or many years after the onset of injury .Liver injury and healing may also occur without even clinical detection. Liver histopathology remains a mainstay in the diagnostic workup of most liver diseases. Liver autopsies are a wonderful learning tool for clinicians as well as pathologists. They help in formulating exact liver disease burden in the population .Present study was conducted between the period of 2008 - 2012 consisting of 154 cases. Fatty change liver (Steatosis) was found to be the most common disease entity followed by hepatitis.

Keywords


Fatty Change (Steatosis), Hepatitis, Cirrhosis

References