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The Role of MiRNA in Breast Cancer


Affiliations
1 Department of General Surgery, Shanghai Tenth People’s Hospital, school of Medicine, Tongji University, 399 Yanchang Road , Zhabei Area, Shanghai 200072, China
 

MicroRNAs (MiRNAs) constitute 19-25 nulceotide, non-coding RNA that regulate the expression of target genes, mainly at the post-transcriptional level. Breast cancer (BC) is most common cause of death in women accounting for 522,000 in 2012.It has got poor prognosis. In this review, we aim to provide a comprehensive story on miRNA signatures of cancers specially breast cancer.

Keywords

MicroRNA, Therapeutic, Diagnostic, Breast Cancer.
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  • The Role of MiRNA in Breast Cancer

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Authors

Niraj Maskey
Department of General Surgery, Shanghai Tenth People’s Hospital, school of Medicine, Tongji University, 399 Yanchang Road , Zhabei Area, Shanghai 200072, China
Song Hongming
Department of General Surgery, Shanghai Tenth People’s Hospital, school of Medicine, Tongji University, 399 Yanchang Road , Zhabei Area, Shanghai 200072, China
Kamolphatr Bantaokul
Department of General Surgery, Shanghai Tenth People’s Hospital, school of Medicine, Tongji University, 399 Yanchang Road , Zhabei Area, Shanghai 200072, China
Fang Lin
Department of General Surgery, Shanghai Tenth People’s Hospital, school of Medicine, Tongji University, 399 Yanchang Road , Zhabei Area, Shanghai 200072, China

Abstract


MicroRNAs (MiRNAs) constitute 19-25 nulceotide, non-coding RNA that regulate the expression of target genes, mainly at the post-transcriptional level. Breast cancer (BC) is most common cause of death in women accounting for 522,000 in 2012.It has got poor prognosis. In this review, we aim to provide a comprehensive story on miRNA signatures of cancers specially breast cancer.

Keywords


MicroRNA, Therapeutic, Diagnostic, Breast Cancer.

References