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Essential Oil Profiling of Centella asiatica (L.) Urb.-A Medicinally Important Herb


Affiliations
1 St. Thomas’ College (Autonomous), Thrissur, Kerala‐680 001, India
 

The Centella asiatica is known as Gotukola. The essential oil is extracted by Clevenger apparatus. The oil yield from whole plant C. asiatica is 0.8 mL in 1 Kg. The essential oil is analyzed by GC‐MS. There are 43 volatile compounds are identified from essential oil of C. asiatica. P‐Cymene‐(44%) is the predominant compound in essential oil of C. asiatica.

Keywords

Centella asiatica, Essential Oil, GC‐MS Analysis.
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  • Adams RP. (2007). Identification of Essential Oil Components by Gas Chromatography/Mass Spectrometry. 4th edn. Allured Publ. Corp., Carol Stream. IL.
  • Ali MSM. (2008). Analysis of phenolics and other phytochemicals in selected Malaysian traditional vegetables and their activities in vitro. PhD Thesis. University of Glasgow. UK.
  • Chou YK. (2005). Studies on the essential oil constituent from the Hydrocotyle Sibthorpioides Lam. and biological assays. Master’s Thesis. Chung Yuan Christian University. Taiwan.
  • Inamdar PK, Yoele RD, Ghogare AB, De Souza NJ. (1996). Determination of biologically active constituents in Centella asiatica. Journal of Chromatgraphy A, 742, 127-130.
  • Incandela L, Belcaro G, de Sanctis MT, Cesarone MR, Griffin M, Ippolito E. (2001). Total triterpenic fraction of Centella asiatica in the treatment of venous hypertension: a clinical prospective randomised trial using a combined microcirculatory model. Angiology, 52(2), S61-S67.
  • Jain P, Guiquing K, Chuanxun Y, Beibei Z, Risheng J, Yuan Y. (2007). Separation and determination of madecassic acid extracts of Centella asiatica using HPTLC with β-cyclodextrin as mobile phase additive. Chinese Journal of Chromatography, 25, 316-318.
  • Kanchan J, Preeti C. (2013). Therapeutic Efficiency of Centella asiatica (L.) Urb. An underutilized green leafy vegetable: an overview. International Journal of Pharma and Biosciences, 4(1), 135-149.
  • Lee J, Jung E, Kim Y, Park J, Hong S, Kim J, Hyun C, Kim YS, Park D. (2006). Asiaticoside induces human collagen I synthesis through TGF beta receptor I kinase (Tbeta RI Kinase) - independent Smad signalling. Planta Medica, 72(4), 324-328.
  • Liu M, Dai Y, Li Y, Luo Y, Huang F, Gong Z. (2008). Madecassoside extracted from Centella asiatica herbs facilitates burn wound healing in mice. Planta Medica, 74, 809-815.
  • Oyedeji OA, Afolayan AJ. Chemical composition and antibacterial activity of the essential oil of Centella asiatica growing in South Africa. Pharmaceutical Biology, 43(3), 249-252.
  • Pragada RR, Veeravalli KK, Chowdary KPR, Routhu KV. (2004). Cardioprotective activity of Hydrocotyle asiatica L. in ischemia-reperfusion induced myocardial infraction in rats. Journal of Ethnopharmacology, 93(1), 105-108.
  • Shukla A, Rasik AM, Jain GK, Shankar R, Kulshrestha DK, Dhawan BN. (1999). In vitro and in vivo wound healing activity of asiaticoside isolated from Centella asiatica. Journal of Ethnopharmacology, 65, 1-11.
  • Soumyanath A, Zhong YP, Gold SA, Yu X, Koop DR, Bourdette D, Gold BG. (2005). Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in vitro. Journal of Pharmacy and Pharmacology, 57(9), 1221-1229.
  • Subathra M, Shila S, Devi MA, Panneerselvam C. (2005). Emerging role of Centella asiatica in improving age-related neurological antioxidant status. Experimental Gerontology, 57(9), 707-715.
  • Supawan R, Patchanee Y. (2014). Antibacterial, antioxidant and chemical profile of Centella asiatica. Biomedical and Pharmacology Journal, 7(2), 445-451.
  • Van den Dool H , Kratz PD. (1963). A generalization of the retention index system including linear temperature programmed gas liquid partition chromatography. Chromatography, 11, 463-471.
  • Wong KC, Tan GL. (1994). Essential oil of Centella asiatica (L.) Urb. Journal of Essential oil Research, 6(3), 307-309.

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  • Essential Oil Profiling of Centella asiatica (L.) Urb.-A Medicinally Important Herb

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Authors

Santhi C. Francis
St. Thomas’ College (Autonomous), Thrissur, Kerala‐680 001, India
M. T. Thomas
St. Thomas’ College (Autonomous), Thrissur, Kerala‐680 001, India

Abstract


The Centella asiatica is known as Gotukola. The essential oil is extracted by Clevenger apparatus. The oil yield from whole plant C. asiatica is 0.8 mL in 1 Kg. The essential oil is analyzed by GC‐MS. There are 43 volatile compounds are identified from essential oil of C. asiatica. P‐Cymene‐(44%) is the predominant compound in essential oil of C. asiatica.

Keywords


Centella asiatica, Essential Oil, GC‐MS Analysis.

References