South Indian Journal of Biological Sciences

Open Access Open Access  Restricted Access Subscription Access

Antibacterial Activity and Phytochemical Analysis of Selected Bryophytes against Penicillin Resiatant Bacterial Pathogens


Affiliations
1 Research Department of Botany, Scott Christian College (Autonomous), Nagercoil-3, India
2 P.G. Department of Botany and Biotechnology, Bishop Moore College, Mavelikara- 690110, India
 

Resistance to Penicillin drugs is a global concern. Medicinal plant products provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. There is a continuous and urgent need to discover new antimicrobial compounds from the lower plant forms like bryophytes against new and re-emerging drug resistant infectious diseases. In this study, the collected epiphytic bryophytes Pogonatum microstomum (Schwaegr.) Brid, Fissidens brevinervis (Broth.) and Pallavicinia lyelli (Hook) were tested against Penicillin resistant bacterial pathogens. They were extracted by percolation method using various solvents like acetone, ethyl acetate and distilled water. The antimicrobial activity was evaluated against the different penicillin resistant pathogenic bacterial strains using agar well diffusion method. The bryophyte extracts showed remarkable inhibitory activity against bacterial pathogens. The extracts were further screened for phytochemical studies and they revealed the presence of alkaloids, flavonoids, phenol, proteins and amino acids, resins, saponins, steroids, tannins, xanthoproteins and sugars. The antimicrobial activities of bryophytes may be due to the presence of various secondary metabolites, which may enhance at the high altitudes.

Keywords

Antibacterial Activity, Bryophytes, Penicillin Resistance, Phytochemical Screening.
User
Notifications
Font Size

  • Ahmad I, Mehmood J, Mohammad F. (1998). Screening of some Indian medicinal plants for their antimicrobial properties. Journal of Ethnopharmacology, 62,183-193.

  • Barber M. (1961). Methicillin-resistant staphylococci. Journal of Clinical Pathology, 14,385-93.

  • Batish DR, Kohli RK, Singh HP and Saxena DB. (1997). Studies on herbicidal activity of parthenin, a constituent of hysterophorus towards billgoat weed (Ageratum conyzoides). Current Science, 73, 369-371.

  • Bauer AW, Kirby MDK, Sherris JC, Turck M. (1966). Antibiotic susceptibility testing by standard single disc diffusion method. American Journal of Clinical Pathology, 45, 493-496.

  • Benner EJ, Kayser FH. (1968). Growing clinical significance of methicillin-resistant Staphylococcus aureus. Lancet, 2,741-4.

  • Chambers HF. (1999). Penicillin-binding protein-mediated resistance in Pneumococci and Staphylococci. Journal of Infectious Diseases, 179, S353-S359.

  • Chaudhary BL, Kumar P. (2011). Antibacterial activity and preliminary phytochemical screening of epiphytic moss Stereophyllum ligulatum Jaeg. International Journal of Pharma and Bio Sciences, 2(4), 674-681.

  • Chobot V, Kubicova L, Nabbout S, Jahodar L, Vytlacilova J. (2006). Antioxidant and free radical scavenging activities of five moss species. Fitoterapia, 77, 598-600.

  • Dulger B, Yayintas OT, Gonuz A. (2005). Antimicrobial activity of some mosses from Turkey. Fitoterapia, 76, 730-732.

  • Eloff JN. (1998). Which extract should be used for the screening of antimicrobial components from plants. Journal of Ethnopharmacology, 60, 1-8.

  • Forrest LL, Davis EC, Long DG, Crandall-Stotler BJ, Clark A, Hollingsworth ML. (2006). Unraveling the evolutionary history of the liverworts (Marchantiophyta):multiple taxa, genomes, analyses. Bryologist, 109, 303-334.

  • Kenneth VIR. (2009). New antimicrobial agents for the treatment of bacterial infection in cancer patients. Hematological Oncology, 27, 107-114.

  • Kumaraswamy MV, Satish S. (2008). Antioxidant and anti-lipoxygenase activity of Thespesia lampas Dalz & Gibs. Advances in Biological Research, 2, 56-59.

  • Locher CP, Burch MT, Mower HF, Berestecky H, Davis H, Van Polel B, Lasure A, Vander Berghe DA, Vlieti-Nick AJ. (1995). Anti-microbial activity and anticomplement activity of extracts obtained from selected Hawaiian medicinal plants. Journal of Ethnopharmacology, 49, 23-32.

  • Panghal M, Kaushal V, Yadav JP. (2011). In vitro antimicrobial activity of ten medicinal plants against clinical isolates of oral cancer cases. Annals of Clinical Microbiology and Antimicrobials, 10, 21.

  • Sabovljevic A, Sokovic M, Sabovljevic M, Grubisic D. (2006). Antimicrobial activity of Bryum argenteum. Fitoterapia, 77, 144-145.

  • Sanjay G, Noresah MS, Arvind B, Chandra PK. (2010). Influence of climate change on production of secondary chemicals in high altitude medicinal plants: Issues needs immediate attention. Journal of Medicinal Plants Research, 4(18), 1825-1829.

  • Sofowora A. (1982). Medicinal plants and traditional medicine in Africa. John Wiley and Sons Ltd.

  • WHO. (1994). WHO meetings–antimicrobial resistance, retrieved 22 February, 2011 from http://whqlibdoc.who.int/hq/1995/WHO CDS BVI 95.7.pdf

  • Umadevi M, Sampath Kumar KP, Debjit BS, Duraivel. (2013). Traditionally used anticancer herbs in India. Journal of Medicinal Plants Studies, 1(3), 56-74.


Abstract Views: 317

PDF Views: 8




  • Antibacterial Activity and Phytochemical Analysis of Selected Bryophytes against Penicillin Resiatant Bacterial Pathogens

Abstract Views: 317  |  PDF Views: 8

Authors

Prasanth G. Williams
Research Department of Botany, Scott Christian College (Autonomous), Nagercoil-3, India
M. Reginald Appavoo
Research Department of Botany, Scott Christian College (Autonomous), Nagercoil-3, India
N. D. Brijith Lal
P.G. Department of Botany and Biotechnology, Bishop Moore College, Mavelikara- 690110, India
Athira Aravind
P.G. Department of Botany and Biotechnology, Bishop Moore College, Mavelikara- 690110, India
G. Prakash Williams
P.G. Department of Botany and Biotechnology, Bishop Moore College, Mavelikara- 690110, India

Abstract


Resistance to Penicillin drugs is a global concern. Medicinal plant products provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. There is a continuous and urgent need to discover new antimicrobial compounds from the lower plant forms like bryophytes against new and re-emerging drug resistant infectious diseases. In this study, the collected epiphytic bryophytes Pogonatum microstomum (Schwaegr.) Brid, Fissidens brevinervis (Broth.) and Pallavicinia lyelli (Hook) were tested against Penicillin resistant bacterial pathogens. They were extracted by percolation method using various solvents like acetone, ethyl acetate and distilled water. The antimicrobial activity was evaluated against the different penicillin resistant pathogenic bacterial strains using agar well diffusion method. The bryophyte extracts showed remarkable inhibitory activity against bacterial pathogens. The extracts were further screened for phytochemical studies and they revealed the presence of alkaloids, flavonoids, phenol, proteins and amino acids, resins, saponins, steroids, tannins, xanthoproteins and sugars. The antimicrobial activities of bryophytes may be due to the presence of various secondary metabolites, which may enhance at the high altitudes.

Keywords


Antibacterial Activity, Bryophytes, Penicillin Resistance, Phytochemical Screening.

References