Research Journal of Science and Technology

Nidhi Rao ¹, Sandhya Mittal ¹

Affiliations
1 Suresh Gyan Vihar University, Jaipur, IN

Abstract

The use of plants in healing of dermatophytes, burns along with infectious diseases is frequent in conventional medicine. The expansion of new antimicrobial agents against defiant pathogens is of escalating interest. Curcuma longa (turmeric) is a diminutive rhizomatous perennial herb of Zingiberaceae (Ginger family) originates from south eastern Asia, mainly from India. It has an elongated history of therapeutic uses as it is credited with a diversity of imperative beneficial properties. Therefore, the methanolic extract of Curcuma longa used locally in folk medicine was evaluated for antibacterial activity against different bacteria i.e. Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum by disc diffusion method. When screening for antimicrobial activity, the results were expressed in terms of the diameter of the inhibition zone: The maximum efficacy of methanolic extract was showed against Shigella flexneri and Candida albicans.

Keywords

Curcuma longa, Antibacterial Activity, Antifungal Activity, Plant Extract.

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Sandhya Mittal ¹, Nidhi Rao ², Sudhanshu ², Ekta Menghani ³

Affiliations
1 Suresh Gyan Vihar University, Jagatpura, Jaipur, IN
2 Suresh Gyan Vihar University, Jaipur, IN
3 Mahatma Gandhi Institute of Applied Sciences, JECRC Campus, Jaipur, IN

Abstract

The present study has been designed with the objective to examine the methanol extract of Tectona grandis L. leaves (family Verbenaceae). In order to investigate its antimicrobial potential against strains of Shigella flexneri, Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus vulgaris, Enterobacter aerogenes, Aspergillus niger, Candida albicans, Trichophyton rubrum. The methanolic extract was found to be the most effective and showed antimicrobial activity against the organisms tested. The zone of inhibition (mm) at various concentrations of methanolic extract of Tectona grandis L. was found in the range 50mg/20disc - 200mg/20disc on tested all the test organisms. The antimicrobial activity was more significant against Salmonella typhi i.e. 21.33 mm zonetion. The study revealed the methanol extract of Tectona grandis L. leaves against microbes.

Keywords

Antibacterial Activity, Tectona grandis L. Methanolic Extract.

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