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Yadav, V. C.
- Therapeutic Efficacy of Third Generation Cephalosporin, Against Ampicillin and Chloramphenicol Resistant Haemophilus Influenzae
Abstract Views :218 |
PDF Views:2
Authors
V. C. Yadav
1,
V. Ravi Kiran
1
Affiliations
1 Microbiology Department, Govt. Medical College, Jagdalpur (CG), IN
1 Microbiology Department, Govt. Medical College, Jagdalpur (CG), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 4 (2011), Pagination: 150-153Abstract
Haemophilus Influenzae type b is an important cause of meningitis in child below two years of age. In many causes treatment is empiric and there is a lack of understanding of resistant issues with this bacterium. This study was aimed to determine the therapeutic efficacy of ceftriaxone and ceftazidime in comparison to chloramphenicol and ampicillin. The mean bacterial colony counts in cerebrospinal fluid were unchanged or slightly increased with ampicillin or chloramphenicol while the mean bacterial colony counts in CSF were reduced by 92% (-3.37 log10 CFU/ml) on 92% (-4.30log 10 CFU/ml) after a single dose of ceftazidime and ceftriaxone.Keywords
Meningitis, Ceftriaxone, Chloramphenicol H. Influenzae, CSF.
References
- Timothy F. Morphy Harrisons Principle of internal medicine 17th 923
- Thomas W.J, J.W. Mc Reynolds, C.R Mock and D.W Balley.1974. Ampicillin resistant Haemophilus Influenzae meningitis Lancet 313
- Dacey. R.G and M.R Sande 1974. Effect of probenccid on cerebrospinal fluid concentration of penicillin and cephalosporin derivatives Antimicrob agents chemotherapy 6: 437-441
- Ananthanarayan R Yayaram paniker C K text book of Microbiology 8th 36-332
- Smith A L 1983Antibiotic resistant in Haemophilus Influenzae pediatric infection Dis 2.352-355.
- Thrupp L D Greene G R uchiyama, N., D B Vitts .1982 meningitis due to haemkohilius Influenzae type b resistant to ampicillin and chloramphenicol J pediatric g7 :421-424.
- Isburg C.D, J.E Kenny and R H Micheels 1980 meningitis due to haemophilus Influenzae type b resistant to both ampicillin and chloramphenicol pediatrics 66: 14-16.
- Sherertz R J, M.A., O.Zake, R.G Dacey, J A Bodine, and I J Stransbangh factors influencing the penetration of antimicrobial agents into the cerebrospinal fluid of experimental specimen, Scand J Infect. Dis (14) 160-163.
- Jean F Venny Carroll D Isburg, Richard meningitis due to H Influenzae type b resistant to both Ampicillin and chloramphenicol pediatrics Vol 66-14-16
- Markowitz .S.M. Isolation of Ampicillin - resistant ,non Beta lactamase producing strain of H. Influenzae, Antimicrob agents chemother. 17:80-83
- Improved medium for antimicrobial susceptibility testing of haemophilus Influenzae. J.H Jorgensen, J S Redding L a Maher and a W Howell. J. Clinical microbiology -1987. 2105-2113.
- Sigue Ringertz, Barbro Olsson. Lilyequist and Goran Kronvall. Antimicrobial susceptibility testing of Haemophilus Influenzae Improvement of Accuracy of the Disc diffusion test. Journal of antimicrobial chemotherapy Volume 26,479-489.
- Slack M P E, Medical microbiology greenwood, Slack Pendtherer, barer, seventeenth edition 31, 318-324.
- A. J. Howard, Catherine A. Isan ( Mackie and Mc Cartney - practical Medical Microbiology)- 14th edition 25:449.
- Perfect J R., S.R land and D T Durack. 1980 Comparison of Cotrimoxazole, ampicillin and chloramphenicol in treatment of experiment Haemophilus Influenzae type b meningitis. Antimicrob Agents Chemother 17: 43-48.
- Ubukata, J 2003 Problems associated with high prevalence of Multidrug resistant bacteria in patients with community - Acquired infection. J infect. Chemotherapy 9:285-91.
- Simasathein, S.C Duangmani and P. Escheverria.1980 Haemophilus Influenzae type b resistant to ampicillin and chloramphenicol in an orphanage in Thailand. Lancet 1214-1217.
- Strausbaugh, L J., C.D Mandaleris and M.A. Sande. 1977. Cefamandole and Ampicillin therapy in experimental Haemophilus Influenzae meningitis J Infect. Dis 135: 210-216.
- Robert P Rennie and Khalid H. Ibrahim., antimicrobial Resistance in Haemophilus Influenzae: how Can We prevent th Inevitable? Commentary on Amtimicrobial Resistance in H. Influenzae based on Data from the Targeted surveillance program. CID . Oxford journal. 2005:41.
- Hasegawa K, Chiba N, Kobayashi R, et al. Rapidly increasing prevalence of b-lactamase-nonproducing ampicillin-resistant Haemophilus Influenzae type b in patients with meningitis. Antimicrob Agents Chemother 2004; 48:1509-14.
- Ubukata, K., 2001 three Years of surveillance of invasive Haemophilus influenzae by the study group for community Acquired infections Jpm J. antibiotic (54:72-79)
- A Fine Needle Aspiration and Imprint Cytodiagnosis of Breast Lumps
Abstract Views :368 |
PDF Views:2
Authors
Affiliations
1 Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
2 Dept. of Microbiology , Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
1 Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
2 Dept. of Microbiology , Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 4 (2012), Pagination: 228-232Abstract
Back ground: Cancer incidentally, is the biggest killer in India, after heart disease and it is estimated that there are 1.5 - 2 million cases at any given point in time.
Objective: To document the diagnostic accuracy of fine needle aspiration and imprint cytodiagnosis in breast lumps.
Material and methods: Nineteen patients attending Surgical O.P.D. of a tertiary hospital were included in the study.
Statistical Analysis: Expressed in simple terms of proportion.
Findings: 84.21 and 94.73 percent were the accuracy rate of FNAC and Imprint cytodiagnosis respectively. There were 10.52 and 5.26 percent false negative and 5.2 and zero percent false positive rates were recorded through FNAC and Imprint cytodiagnosis respectively.
Conclusion: It was concluded that F.N.A.C. and Imprint cytodiagnosis are valuable tools in the management of suspected malignancy and should be recommended as a routine practice.
Keywords
Lumps, Cytodiagnosis.References
- India to host trials for viruses to treat cancer; The Times of India, New Delhi: 6th.March, 2010: pp 09.
- Garg Narendra K. Evaluation of the impact of emesis and emesis plus purgation therapy; Research J. Pharmacology and Pharmacodynamics: 2 (2) March - April 2010; 201-202.
- Franzeh S. and Zajicek J.; Aspiration biopsy in diagnosis of palpable lesion of the breast - "Acta Cyto 20; 553-555 (1976)".
- Webb A.J.; The use and reliability of lymphoid cytodiagnosis in surgical practice (Abstract) "Acta Cytol. 22: 176-177 (1978)".
- Dudgeon L.S. and Barret N.R.; Bhalerao: "Ind. Journal Surgery; 41; 11-15".
- Zajdela, A.: The value of aspiration cytology in diagnosis of breast cancer "Cancer 35: 499-506 (1975)".
- Mouriquand J. and Durgent M.: Cited by Tribe 26 (1957).
- Marsan C. and Bertani B.: Cited by Tribe 26 (1960).
- Singh A. et. Al.: Evaluation of imprint cytodiagnosis by imprint method in breast tumour-'Ind. J. of Path. And Microbiol. 25 (1): 29-33 (1982)".
- Boqui E. and Krevzer C.: Aspiration biopsy cytology mammography and Clinical exploration-"Acta Cyto 35-45 (1981)".
- Soderstone: Cited by Webb 29 (1969).
- Bansal A.K. Chandorkar R.K., Knowledge, Belief, and Practice: A study of Tribal Mother about feeding of infants, Tribal Health Bulletin (I.C.M.R.) 1993; 2:3-4.
- Garg Narendra K.and Bansal A.K. Management of information system in context of health care delivery .J of Ravishanker University; Vol 14:No. B (Science) 2001:35-40.
- Bansal A.K and Garg Narendra K, Information, Education, Communication in context oh reproductive and child health including HIV/AIDS. J. of Ravi Shanker University; Vol 14 No. B (Science) 2001:28-34.
- Zajick, I. et. Al.; Aspiration biopsy of mammary tumour in diagnosis and research: A critical review of 2200 cases (1967).
- Bansal A.K.,Agarwal Ashok K.,Govila A.K. :Status of Girl Child amongst tribes and non tribes in the un reached rural India; J of Ravishankar University; Vol. 11-12 :No.B (Science) 1998- 99 :31-36..
- Alfia Fatima, Bansal A.K., Shamsuddoha, Ratre, H.L. et. al. Leprosy elimination in district Sarguja; J of Ravishankar University: Vol.18 :No. B (Science) 2006; pp 61-68.
- The Cytological Diagnosis of Prostate Cancer
Abstract Views :204 |
PDF Views:2
Authors
Affiliations
1 Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
1 Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 4 (2012), Pagination: 241-244Abstract
Background: More than two thirds of all cancer deaths occur in low and middle income countries. It is estimated that there are 1.5 -2 million cases at any given point in time.
Objective: Early and accurate diagnosis of cancer patients. Material and methods: Eighteen cases after clinical diagnosis were subjected to FNAC and Imprint cytodiagnosis by perineal route and needle with stylus and Histology.
Findings: The accuracy rate of both FNAC and Imprint cytodiagnosis was 100%. There were no false results.
Conclusion: A very important benefit of FNAC and Imprint cytology in prostatic diseases is reduction of time interval between needle biopsy of prostate and surgery i.e. surgery can be performed after one hour of biopsy.
Keywords
Democratic Alliance, Key Players.References
- India to host trials for viruses to treat cancer: The Times of India, New Delhi .March 6, 2010; pp 9.
- Garg Narendra K. Evaluation of the impact of emesis and emesis plus purgation therapy; Research J. Pharmacology and Pharmacodynamics: 2 (2) March - April 2010; 201-202.
- Bamforth J.: Cytological diagnosis in medical practice - "Churchill London (1966)
- Dudgeon L.S. and Barret N.R.: The examination of fresh tissue by the wet film method Brt.J.Surg.22; 4-22(1934).
- Godwin J. T.: Rapid diagnosis of surgical specimen; Acta Cytol: 20; 11-115 (1964).
- Bansal A.K. Chandorkar R.K., Knowledge, Belief, and Practice: A study of Tribal Mother about feeding of infants, Tribal Health Bulletin (I.C.M.R.) 1993; 2:3-4.
- Garg Narendra K. and Bansal A.K. Management of information system in context of health care delivery .J of Ravishanker University; Vol 14:No. B (Science) 2001:35-40.
- Bansal A.K and Garg Narendra K, Information, Education, Communication in context of reproductive and child health including HIV/AIDS. J. of Ravi Shanker University; Vol 14 No. B (Science) 2001:28-34.
- Alfia Fatima, Bansal A.K., Shamsuddoha, Ratre, H. L. et. al. Leprosy elimination in district Sarguja ; J of Ravishankar University: Vol.18 :No.B (Science )2006; pp 61-68.
- Third-hand smoke can cause cancer too: The Times of India, New Delhi, Thursday, February 11, 2010; pp 16.
- Some Observations on Study of F.N.A.C. and Imprint Cytodiagnosis in Lymph Adenopathy
Abstract Views :241 |
PDF Views:0
Authors
P. Pandey
1,
V. C. Yadav
2,
K. K. Singh
3,
A. K. Bansal
3,
K. L. Azad
3,
Sashi Kala Kashyap
3,
P. K. Shrivastav
3
Affiliations
1 Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
2 Dept. of Microbiology, Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
3 Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
1 Govt. Medical College, Jagdalpur, Bastar (C. G.) 494001, IN
2 Dept. of Microbiology, Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
3 Govt. Medical College, Jagdalpur, Bastar (C.G.) 494001, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 5 (2012), Pagination: 285-289Abstract
Objective: To evaluate the role of Fine needle Aspiration Cytology and Imprint Cytodiagnosis in the diagnosis of Lymphadenopathy.
Materials and Methods: Eighteen patients having lumps as a clinical diagnosis, attended Surgical outdoor of a hospital attached to a medical college were included in the study. Lumps were subjected to fine needle aspiration cytology, excision then imprint smears, specimen thus obtained subjected to histological examination.
Statistical analysis: were expressed in terms of simple proportion
Findings: 94.44% and 5.55% accuracy and false negativity rate respectively was noted in both F.N.A.C. and Imprint cytodiagnosis, similarly false positivity rate was zero.
Conclusion: Fine needle aspiration cytology and imprint, both are simple, safe, reliable, easily learnt techniques and they save a lot of time, money, hospital beds stay and above all anxiety to the patient.
Keywords
Pegs, Media Mix.References
- Non-communicable diseases drained India of $ 9bn in 2005; The Times of India, N. Delhi, dated 30.4.2011: pp 07.
- Garg Narendra K. Evaluation of the impact of emesis and emesis plus purgation therapy; Research J. Pharmacology and Pharmacodynamics: 2 (2) March - April 2010; 201-202.
- Webb A.J.: The use and reliability of LYMPHOID CYTODIAGNOSIS IN Surgical practice (Abstract) "Acta Cytol: 22; 176-177:1978".
- Chitale D.R. Mehta and Bhalerao S.L.; Indian J of Surgery; 41:11-15.
- Jagla K. et. al.: Imprint cytology of axillary lymph node in breast cancer for rapid intra-operative diagnosis - Fortschr Med. 96 (26/27):1366-68 (1978).
- Fienberg M.R.: Differential Diagnosis of Malignant Lymphoma by Imprint Cytology: Acta Cytol .24:16-25 (1980).
- Quill D.S. et. al. Lymph node imprint cytology for rapid assessment of axillary L. node metastases in breast cancer: Br.J.Surg.71 (6):454-455(1984).
- Bansal A.K. Chandorkar R.K., Knowledge, Belief, and Practice: A study of Tribal Mother about feeding of infants, Tribal Health Bulletin (I.C.M.R.) 1993; 2:3-4.
- Garg Narendra K. and Bansal A.K. Management of information system in context of health care delivery J of Ravishanker University; Vol 14:No. B (Science) 2001:35-40.
- Bansal A.K and Garg Narendra K, Information, Education, Communication in context oh reproductive and child health including HIV/AIDS. J. of Ravi Shanker University; Vol 14 No. B (Science) 2001:28-34
- India to host trials for viruses to treat cancer: The Times of India, N.Delhi:6.3.20011:pp 09.
- Alfia Fatima, Bansal A.K., Shamsuddoha, Ratre, H.L. et. al. Leprosy elimination in district Sarguja ;J of Ravishankar University :Vol.18 :No. B (Science) 2006; pp 61-68