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Chanda, Smriti Rekha
- Anti-Inflammatory Activity of a Protease Extracted from the Fruit Stem Latex of the Plant Artocarpus heterophyllus Lam
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Authors
Affiliations
1 Department of Pharmacy, Girijananda Chowdhury Institute of Pharmaceutical Science, Hathkhowapara, Azara, Guwahati - 781017, Assam, IN
2 Department of Pharmacy, Gupta College of Technological Sciences, Asansol- 713301 West Bengal, IN
1 Department of Pharmacy, Girijananda Chowdhury Institute of Pharmaceutical Science, Hathkhowapara, Azara, Guwahati - 781017, Assam, IN
2 Department of Pharmacy, Gupta College of Technological Sciences, Asansol- 713301 West Bengal, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 2 (2009), Pagination: 70-72Abstract
The anti-inflammatory activity of the new protease fraction Artocarpain-H extracted from the fruit stem latex of the plant Artocarpus heterophyllus Lam. was evaluated using Carrageenan induced rat paw oedema and Cotton pellet-induced granuloma model. The Artocarpain-H dose dependently inhibited carrageenan induced rat paw edema. It also showed reduction on the granuloma weight in the cotton pellet granuloma method.. In the present investigation, as the test drug is effective in both models of inflammation, there is a possibility that these drugs may be effective in acute and chronic inflammation.Keywords
Protease, Artocarpain-H, Rat Paw Oedema, Granulom.
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