Research Journal of Pharmacology and Pharmacodynamics

Anil G. Markandeya ¹, Narayan P. Firke ¹, Suneeti S. Gore ², Sunita Salunke-Gawali ³, Shirish S. Pingale ⁴

Affiliations
1 Department of Chemistry, Fergusson College, Pune 411 004, IN
2 Department of Microbiology, Fergusson College, Pune 411 004, IN
3 Department of Chemistry, University of Pune, Pune 411 004, IN
4 Department of Chemistry, ACS College, Narayangaon, Pune 410 504, IN

Abstract

In present article we report in vitro antimicrobial activity of Celocia argentea leaves extract against human pathogenic bacteria. Antibacterial assay was performed by disc diffusion method for Staphylococcus aureus, Bacillus subtilis, Proteus vulgaris and Pseudomonas aeruginosa. These bacteria were isolated and purified by streak plating method. The extracts of C. argentea leaves in carbon tetrachloride, chloroform, cyclohexane, ethanol, ethyl acetate and n-hexane were found to have varied levels of antibacterial activity against studied bacteria. Although, C. argentea has been known for its active phytochemicals including phenols, tannins and flavonoids as major constituents found scarce as antibacterial source.

Keywords

Anti-Bacterial Activity, Celocia argentea, Soxhlet Extraction, Staphylococcus aureus, Bacillus subtilis, Proteus vulgaris, Pseudomonas aeruginosa.

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