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Anuradha, R.
- Potential of Carica papaya Against Gentamicin Induced Nephrotoxic Rats
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Authors
S. Saranya
1,
R. Anuradha
1
Affiliations
1 PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Mannargudi-614001, Tamil Nadu, IN
1 PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Mannargudi-614001, Tamil Nadu, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 1 (2012), Pagination: 17-20Abstract
The present study was desined to evaluate the nephroprotective effect of ethanolic extracts of seeds of Carica papaya against gentamicin induced nephrotoxicity in albino rats. Oral administration of gentamicin (5mg/100g body weight/day) shows the significantly reduction in serum urea, uric acid, creatinine and protein, level were significantly decreased when compared to the control rats. Ethanolic extracts of seeds of Carica papaya administration (40 mg/kg b. wt/day) brought about the significant changes in biochemical parameters. The present work indicates that the Carica papaya extracts has showed their protective role against gentamicin induced nephrotoxicity and its more effective in preventing kidney damage that treating it.Keywords
Nephrotoxicity, Renal Markers, Gentamicin, Carica papaya.
References
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- Antinephrotoxic Effect of Boerhaavia diffusa L. Root on Lead Acetate Induced Nephrotoxicity in Male Albino Rats
Abstract Views :281 |
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Authors
N. Vaidegi
1,
R. Anuradha
1
Affiliations
1 PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Sundarakkottai, Mannargudi-614016, Tamil Nadu, IN
1 PG and Research Department of Biochemistry, Sengamala Thayaar Educational Trust Women's College, Sundarakkottai, Mannargudi-614016, Tamil Nadu, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 6 (2012), Pagination: 353-356Abstract
Many Nephroprotective herbal preparations have been recommended in Indian systems of medicine for the treatment of neprotic disorders. Protective action of Boerhaavia diffusa extract (BDE) was evaluated in the animal model of Nephrotoxicity induced by lead acetate. Kidney marker enzymes and antioxidant enzymes were changed in lead acetate intoxicated rats. Boerhaavia diffusa extract brought about a moderate changes in the activities of all the above said levels. The present observation suggested that the treatment with Boerhaavia diffusa extract enhance the recovery from lead acetate induced nephrotic damage due to its nephroprotective activity.References
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- Immunostimulatory Activity of Rosa centifolia in Azathioprine Induced Rats
Abstract Views :250 |
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Authors
Affiliations
1 PG and Research Department of Biochemistry, S.T.E.T. Women's College, Sundarakkottai, Mannargudi -614001, Tamil Nadu, IN
1 PG and Research Department of Biochemistry, S.T.E.T. Women's College, Sundarakkottai, Mannargudi -614001, Tamil Nadu, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 4, No 4 (2012), Pagination: 210-212Abstract
The ethyl acetate extract of Rosa centifolia was administered orally to evaluate the immunostimulant activity against azathioprine induced immunosuppression. Evaluation was done by measuring the changes in hematological and enzymatic parameters. Results of all parameters exhibited immunostimulatory activity in Rosa centifolia.Keywords
Rosa centifolia, Azathioprine, Hematological Changes, AST, ALT, Vitamin C.References
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