Research Journal of Pharmacology and Pharmacodynamics

B. Prathib ¹, Nikhil P. Varghese ¹, J. H. Virupaksha ¹, I. J. Kuppast ¹

Affiliations
1 Department of Pharmacology, National College of Pharmacy, Balraj Urs Road, Shivamogga (Dist) - 577201, Karnataka, IN

Abstract

Ichnocarpus frutescens R.Br (Family: Apocyanaceae) is an ever green medicinal herb found almost throughout Asia and other regions. The whole part of Ichnocarpus was (ischolar_main, flowers and leaves) reported to use for various medical illness such as, demulcent, syphilis, loss of sensation and hemiplegia, head aches fevers, wounds between fingers tonic, diaphoretic, diuretic and dyspepsia and skin troubles. It is mainly administered with milk for diabetes mellitus, excretion of the stone in the bladder and purification of blood. Phytochemical studies on the various parts of Ichnocarpus have revealed the presence of phenylpropanoids, phenolic acids, carbohydrates, saponins, proteins, amino acids, coumarines, alkaloids, flavonoids, sterols and pentacyclic triterpenoids. Pharmacological investigations have demonstrated that Ichnocarpus possess antiinflammatory, analgesic, antipyretic, membranestabilizer, hepatoprotective, antiurolithiatic, antimicrobial, antidiabetic, cardioprotective, antioxidant, antihyperlipidemicand cytoprotective activities.

Keywords

Ichnocarpus frutescens, Antibacterial, Antidiabetic, Antioxidant.

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Nikhil P. Varghese ¹, T. Shekshavali ¹, B. Prathib ¹, I. J. Kuppast ¹

Affiliations
1 Department of Pharmacology, National College of Pharmacy, Shivamogga -577201, Karnataka, IN

Abstract

Plants are the principle source of raw materials for plant based medicine since ancient times. The traditional herbal medicines are receiving great importance in the health care sector. In Indian system of medicine i.e, ayurveda, one of the plant Naravelia zeylanica (Linn) DC belonging to family ranunculaceae has been used in the treatment of helminthiasis, dermatopathy, leprosy, rheumatalgia, odontalgia, colic inflammation, wounds and ulcers. It is distributed throughout india mainly in warm regions of Eastern Himalayas, Assam, Bengal, Bihar and greater parts of Deccan Peninsula. The aerial parts of Naravelia zeylanica traditionally used in vitiated vata, pitta, inflammation, skin diseases. The present study revel the pharmacological activates and presence of phytoconstituents likealkaloids, flavonoids, phenolics, terpenoids, etc. in Naravelia zeylanica.

Keywords

Ulcer Index, Antioxidant, Flavonoids, Ranunculaceae.

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