Refine your search
Collections
Co-Authors
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Chalichem, Nehru Sai Suresh
- Pharmacological Evaluation of Antiasthmatic Activity of Tamarindus indica Seed
Abstract Views :302 |
PDF Views:1
Authors
R. Suresh
1,
Ganesh Pandhari Mhaske
2,
Nehru Sai Suresh Chalichem
2,
Ashok Kumar Javvadi
2,
D. Benito Johnson
2,
R. Venkatanarayanan
2
Affiliations
1 Department of Pharmacology, R. V. S. College of Pharmaceutical Science, 242, Trichy Road Sulur, Coimbatore-641 402., IN
2 Department of Pharmacology, R. V. S. College Pharmaceutical Science, Sulur, Coimbatore-641 402, IN
1 Department of Pharmacology, R. V. S. College of Pharmaceutical Science, 242, Trichy Road Sulur, Coimbatore-641 402., IN
2 Department of Pharmacology, R. V. S. College Pharmaceutical Science, Sulur, Coimbatore-641 402, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 3 (2011), Pagination: 115-122Abstract
Practical experience and several modern research studies have shown that therapy using plant is better than using synthetic chemicals. According to ayurvedic folklore the Tamarindus indica Linn was mentioned for several ailments including asthma (kirtikar et al; 2001) the present study was planned to know the anti asthmatic activity of methanolic extract of this plant at different stages or different types of asthma using various evaluation models like, isolated goat tracheal chain preparation, bronchial hyperactivity, clonidine induced catalepsy in guinea pig, mast cell degranulation, milk induced leucocytosis in mice, milk induced eosinophilia in mice, passive paw anaphylaxis, and its activities such as bronchodilating, antihistaminic, anti inflammatory , anti allergic, mast cell stabilizing and adaptogenic activities were confirmed presenting the scope of plant for further studies. The data was analyzed by student't' test or one way ANOVA followed by Dunnett test. P≤0.05 was considered as significant.Keywords
Tamarindus Indica Linn., Catalepsy, Leukocytosis, Anaphylaxis, Degranulation.
References
- Wardlaw et al.,.New insight into the relation between airway inflammation and asthma. Clinical science, 2002; 103: 201-11.
- Oliver N, Gerald h, and Gert K,. Immunological and clinical changes in allergic asthmatics following treatment with omalizumab. Int Arch Allergy Immunol.2003;131: 46-52.
- Ryland P.B., Guha K, and Thomas M.R.,. Difficult to management of Asthma. Post graduate medicine. 2000; 108(6): 2-11.
- Casstillo.J.C. De-Beer, E.J., 1947. The tracheal chain-1. A preparation for the study of antispasmodics with particular reference to bronchodilator drugs. J. Pharmacol. Exp. Ther. 1947;90: 104-109.
- Kulshrestha, S., Misra, S.S, Sharma A.L., Sharma, L., Singhal, D.,. Response of the goat trachea to some autonomic drugs. Ind. J. Pharmacol.1983; 15(2): 107-109.
- Naj chaudhary, A.K., Lahari, S.C.,. Use of goat trachea isolated tracheal chain preparation. Ind. J. Pharmacol. 1974;6: 149-51.
- Ghosh, M.N. Fundamental of Experimental Pharmacology Scientific Book Agency Calcutta, 1984; 2nd ed., p.115-21.
- Singh, S., Majumdar, D.K.,. Anti-inflammatory activity of cium sancyum oil and Flax seed oil. Ind J Exp Biol. 1990;35:380-383.
- Tripathi R.M., Das, P.K.. Studies on Antiasthmatic and Antianaphylactic activity of Albizzia lebbeck. Ind. J. Pharmacol. 1977;9(3): 189-194.
- Mitra, S.K. Antiasthmatic and Antianaphylactic effect of E-721B, an herbal formulation, Ind. J. Pharmacol. 1999; 31: 133-137.
- Jadhav, J.H., Balsara J.J., Chandorkar,A.G. Involvement of histaminergic mechanisms in cataleptogenic effect of clonidine in the mice. J.Pharm.Pharmacol 1983;35:671-73.
- Muley, M.P., Balsara, J.J., Chandorkar. Effect of L-histidine pretreatment on haloperidol induced catalepsy and methamphetamine stereotype in mice. Ind. J. Pharmacol, 1983;1164: 293-300.
- Schwartz, J.C.. Annual review of Pharmacology and Toxicological; edited by Elliot, H.W., George, R., Okun,R., Ann. Reviews. Inc., Palo Alto. 1997; 4th ed., 325-339.
- Balsara, J.J., Chandorkar, A.G., Jadhav, J.H. Involvement of histaminergic mechanisms in the cataleptogenic effect of clonidine in mice. Journal of Pharm. Pharmacol 1983;35:671-83.
- Ferre, S., Guix, T., Prat,G., Jane,F., Casas, M. Is experimental catalepsy properly measured pharmac Biochem Behav 1990;35:753-7.
- Uvnas, B. Mast cells and Histamine release. Indian J Pharmacol. 1969; 1 (2): 23-25.
- Geetha, V.S., Viswanathan, S., Kameswaran, L. Comparision of total alkaloids of Tylophora indica and Disodium cromoglycate on mast cell stabilization. Indian J Pharmacol 1981;13: 199-201.
- Lakdawala, A.D., Dadkar, N.K., Dohadwala A.N. Action of clonidine on the mast cells of rats. J. Pharm. Pharmacol. 1980; 32: 790-791.
- Brekhman,I.I., Dardymov.I.V. New substances of plant origin which increases non specific resistance.Ann.Rev.Pharmac. 1969;9: 419-430.
- Brigden, M.L.. A Practical Workshop For Eosinophilia Postgraduate Med. 1999;3: 105-15.
- Ehright,T., chua,S., Lim, D.J.. Pulmonary eosinophilic syndromes. Ann.Allergy. 1989;62: 277-83.
- Bhargava. K.P., Singh, N. Antistress activity of ocimum sanctum. Indian Journal of Medical Research 1981;73: 443-451.
- Ghai,A.. A textbook of Practical Physiology1987;3rd ed., Jaypee Brothers Delhi. 9.191-92.
- Gokhale,A.B., Saraf, M.N. Bronchoprotective effect of methanolic extract of Tephrosia purpurea in vivo. Indian Drugs 1996; 37(7): 346-347.
- Cua-Lim, F.. Immunological aspects of asthma: Therapeutic implications.1984;2: 15-26.
- Kulkarni, S.K. Biological Distribution of Histamine Receptors. Indian J.Pharmacol 1976; 9(3): 157-159.
- Mengi S, Pungle P, Banavalikar M, and Suthar A. Immunomodulatory activity of bosweliic acids of Boswellia sarrata Roxb. Indian J Exp Biol. 2003;41: 1460-62.