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Panchal, Mayank
- Phytochemical Investigation and Antidiabetic Activity Studies of Moringa oliefera Roots
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Authors
Affiliations
1 Department of Pharmacognosy, Vidyabharti Trust College of Pharmacy, Umrakh, (Gujarat), IN
1 Department of Pharmacognosy, Vidyabharti Trust College of Pharmacy, Umrakh, (Gujarat), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 5 (2011), Pagination: 268-277Abstract
Moringa oliefera Lam. is one of the best known and most widely distributed and naturalized species of a monogenetic family Moringaceae. The ischolar_mains of plant were extracted with ethanol by soxhlet technique and aqueous extract of ischolar_mains are prepared by maceration technique. Both the extracts are subjected to phytochemical screening. Require quantity of alcoholic and aqueous extracts were obtained from the plant which is used as test drug in Streptozotocin induced diabetic model. The present investigation is undertaken to study the effect of the potential hypoglycemic effect of Moringa oliefera Lam. in Streptozotocin (STZ) induced Diabetes Mellitus.Keywords
Antidiabetic activity, Moringa oliefera, Streptozotocin, Glipizide.
References
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- Antidiabetic and Antihyperlipidemic Activity of Roots of Matricaria recutita on Streptozotocin-Induced Diabetic Rats
Abstract Views :232 |
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Authors
Affiliations
1 Dept. of Pharmacology, Vidyabharti Trust College of Pharmacy, Umrakh, IN
1 Dept. of Pharmacology, Vidyabharti Trust College of Pharmacy, Umrakh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 4 (2011), Pagination: 180-183Abstract
The present study was aimed to evaluate the anti diabetic - activity of Matricaria recutita ischolar_mains against Streptozotocin (STZ) induced experimental rats. Ethanolic extract of ischolar_mains of Matricaria recutita was administered to streptozotocin induced rats. Glibenclamide was used as a standard drug. Blood glucose levels were determined after oral administration of a dose of Matricaria recutita (400 mg/kg b. wt) in diabetic groups. Blood glucose levels were determined on 0, 7th, 14th and 21st day after oral administration of ethanolic extracts of Matricaria recutita (400 mg/kg). An ethanolic extract of Matricaria recutita was found to reduce blood sugar in streptozotocin induced diabetic rats. Reduction in blood sugar could be seen from 7th day after continuous administration of the extract. The effect of extracts of Matricaria recutita on serum lipid profile like Total cholesterol, triglycerides, low density, very low density and high density lipoprotein were also measured in the diabetic and non diabetic rats. There was significant reduction in Total cholesterol, LDL cholesterol, VLDL cholesterol and improvement in HDL cholesterol in diabetic rats. These results indicated that Matricaria recutita possesses a hypoglycemic and antihyperlipidemic effect.Keywords
Matricaria Recutita, Glibenclamide, Hypoglycemia, Antihyperlipidemic, Streptozotocin.References
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