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Fatiha, Grifi
- Toxic Effects of Acrolyc Denture Teeth Resin, Lucitone 119 on Animal Model: Rats Wistar
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Authors
Bouaricha Houda
1,
Grifi Fatiha
2,
Berrebbah Houria
1,
Tadjine Aicha
1,
Rouabhi Rachid
3,
Djebar Mohammed-Réda
1
Affiliations
1 Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, DZ
2 Annaba University, Annaba, 23000, DZ
3 N.& L. S. Department, Tebessa University, Tebessa, 12000, DZ
1 Laboratory of Cellular Toxicology, Annaba University, Annaba, 23000, DZ
2 Annaba University, Annaba, 23000, DZ
3 N.& L. S. Department, Tebessa University, Tebessa, 12000, DZ
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 36-40Abstract
This study examines the potential toxic effects of lead compounds of an acrylic resin used in the manufacture of dental bases: the LUCITONE 119. The resin treatment is swallowed by diluting the compound in the drinking water of female Wistar rats. After treatment for 07 days and 21 days, average weights of animals and two organs (liver and spleen) are determined. Meanwhile, cellular blood components (red cells, hemoglobin, hematocrit, platelets, lymphocytes, monocytes and granulocytes) and haematological parameters (MCV, MCH and MCHC) were measured. The results show a disturbance in average weight of rats associated with that of the two organs involved (liver and spleen). Biochemical assays show a significant hematotoxicity mainly on platelets, hematocrit and leukocyte lineage.Keywords
Acrylic Resin, Lucitone119, Wistar Rats, Hematological Toxicity, Blood.
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