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Banji, David
- Vector Control Activity Studies on the Leaf of Zyziphus mauritiana
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Authors
Affiliations
1 Dept. of Pharmacognosy, Nalanda College of Pharmacy, Nalgonda AP, IN
2 Nalanda College of Pharmacy, Nalgonda, A.P., IN
1 Dept. of Pharmacognosy, Nalanda College of Pharmacy, Nalgonda AP, IN
2 Nalanda College of Pharmacy, Nalgonda, A.P., IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 1 (2010), Pagination: 71-74Abstract
The present study was undertaken to evaluate anthelmintic and larvicidal activity of crude ethanolic leaf extract of Zyziphus mauritiana belonging to family Rhamnaceae. Through the preliminary chemical tests it was found that the plant is rich in flavonoids, phenols, steroids and tannins. Pheretima posthuma was used as the test worms. Various concentrations of ethanolic extracts were tested in the anthelmintic screening, which involved determination of time of paralysis (P) and time of death (D) of the worms. Piperazine citrate was included as standard reference and distilled water as control. In the case of larvicidal activity the study was conducted on Culex quniquefasicatus species of mosquito larvae and the rate of larval mortality was calculated. The results indicated that the crude ethanolic extract significantly demonstrated paralysis and also caused death of the helminth especially at higher concentration of 50 mg/ml, as compared to standard reference piperazine citrate. Similarly very optimistic results were observed for Culex quniquefasicatus species of mosquito larvae and LC50 value was calculated as 54.9658.Keywords
Antihelmintic, Larvicidal, Zyziphus mauritiana, Pheretima Posthuma, Culex quniquefasicatus.
References
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- Alpha-Glucosidase Inhibitory Activities of Wrightia tinctoria Roxb and Schrebera swietenoides Roxb Bark Extract
Abstract Views :301 |
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Authors
Affiliations
1 Fathima Institute of Pharmacy, Ramarajupalli, Kadapa, Andhra Pradesh, IN
2 Department of Pharmacognosy, Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, IN
3 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, IN
1 Fathima Institute of Pharmacy, Ramarajupalli, Kadapa, Andhra Pradesh, IN
2 Department of Pharmacognosy, Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, IN
3 Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 22-24Abstract
Alpha glucosidase inhibitory activities of Wrightia tinctoria Roxb and Schrebera swietenoides Roxb ethanol extracts were investigated individually. Wrightia tinctoria Roxb and Schrebera swietenoides Roxb bark extract showed in-vitro inhibitory activity of intestinal alpha glucosidase enzyme maltase. Analysis of data confirms that alpha glucosidase inhibition activity was the maximum at 1500mcg/ml of Wrightia tinctoria Roxb bark and 2000mcg/ml of Schrebera swietenoides Roxb bark. The purpose of study was to know whether Wrightia tinctoria Roxb bark and Schrebera swietenoides Roxb bark extract could reduce intestinal absorption of monosaccharides by inhibiting disaccharide hydrolysis. These results suggest that the Wrightia tinctoria Roxb bark extract and Schrebera swietenoides Roxb bark has little potent alpha glucosidase inhibitory activity individually and would be effective in suppression of elevation in blood glucose.Keywords
Wrightia tinctoria Roxb, Schrebera swietenoides Roxb, Maltase, Acarbose.References
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