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Bharti, D. K.
- Diabetes Macroangiopathy - A Review
Abstract Views :237 |
PDF Views:2
Authors
Affiliations
1 Department of Pharmacology, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Taluka: Purandar, Pune 412301, IN
2 Seth Govind Raghunath Sable College of Pharmacy, Saswad, Taluka: Purandar, Pune 412301, IN
1 Department of Pharmacology, Seth Govind Raghunath Sable College of Pharmacy, Saswad, Taluka: Purandar, Pune 412301, IN
2 Seth Govind Raghunath Sable College of Pharmacy, Saswad, Taluka: Purandar, Pune 412301, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 1, No 2 (2009), Pagination: 45-49Abstract
Diabetes mellitus, a metabolic disorder characterised by high levels of blood glucose, is associated with several vascular complications. Although insulin treatment, oral medications, dietary regulations and exercise can delay the development of diabetic microangiopathy, the development of macroangiopathy cannot be prevented solely by glycaemic control. However, diabetic-macroangiopathy refers mainly to an accelerated form of atherosclerosis. This in turn affects both the coronary and cerebral vasculature, thus increasing the risk of myocardial infarction, angina pectoris and cerebrovascular accidents. Diabetes mellitus in humans and animal models of diabetes are associated with impaired endothelium-dependent relaxation i.e. endothelial dysfunction. Endothelial dysfunction, a surrogate marker for the development of diabetic macroangiopathy.Keywords
Diabetes Mellitus, Endothelial Dysfunction, Hyperglycemia, Oxidative Stress.
References
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- Evaluation of Antioxidant Activity of the Aerial Parts of the Abutilon Indicum (linn) Sweet (Malvaceae)
Abstract Views :236 |
PDF Views:0
Authors
S. B. Datir
1,
A. M. Patel
1,
A. K. Patel
1,
P. P. Patil
2,
F. I. Rohit
2,
V. D. Thorat
2,
D. K. Bharti
2,
A. B. Ganjare
3
Affiliations
1 Department of Pharmacognosy, S. N. D. College of Pharmacy, Yeola, A/P- Babhulgaon, Tal - Yeola, Dist-Nasik, Pin- 423401, Maharashtra, IN
2 Department of Pharmacology, S. N. D. College of Pharmacy, Yeola, (M. S.), IN
3 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, (M. S.), IN
1 Department of Pharmacognosy, S. N. D. College of Pharmacy, Yeola, A/P- Babhulgaon, Tal - Yeola, Dist-Nasik, Pin- 423401, Maharashtra, IN
2 Department of Pharmacology, S. N. D. College of Pharmacy, Yeola, (M. S.), IN
3 Department of Pharmacognosy, Pravara Rural College of Pharmacy, Loni, (M. S.), IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 5 (2010), Pagination: 324-327Abstract
Abutilon indicum (Linn) sweet (Malvaceae) is a weed found on way side and at west place throughout the India, commonly known as Atibala. Phytochemical study of the plant revealed that the plant contains various phytoconstituent like flavonoids, tannins and phenolic compounds. Plant may give antioxidant activity as these phytoconstituents are reported to have antioxidant potential. Antioxidant activity of the various extracts of the aerial parts of A. indicum viz. petroleum ether extract, chloroform extract, methanol extract and aqueous extract was evaluated by using DPPH assay method, ABTS assay method and FRAP assay method. Total phenolic content of all the extracts was also determined. Results showed that methanol extract shows potent antioxidant activity and highest phenolic content.Keywords
Abutilon indicum, DPPH Assay, ABTS Assay, FRAP Assay, Total Phenolic Content.References
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- Datir S. B., Ganjare A. B., Nirmal S. A., Bhawar S. B. and Patil M. J. Antioxidant activity of the aerial parts of Achyranthes aspera Var. Porphyristachya (Wall. Ex Moq) Hook. F. Research Journal of Pharmacognosy and Phytochemistry, (2009), 1 (3),220-223.
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