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Amala Bricey, A.
- Hepatoprotective Effect of Pergularia daemia on Cadmium Chloride Induced Toxicity in Rats
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Authors
Affiliations
1 Department of Biotechnology, J.J college of Arts and Science, Pudukottai, IN
2 School of Life Sciences, Department of Biotechnology, University College of Engineering, JNTU, Kakinada, Andhra Pradesh, IN
3 Department of Biotechnology, Bharathidasan University, Trichy, IN
1 Department of Biotechnology, J.J college of Arts and Science, Pudukottai, IN
2 School of Life Sciences, Department of Biotechnology, University College of Engineering, JNTU, Kakinada, Andhra Pradesh, IN
3 Department of Biotechnology, Bharathidasan University, Trichy, IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 3, No 1 (2011), Pagination: 19-21Abstract
The present study was undertaken to examine the inhibitory effect of the Pergularia daemia on cadmium chloride induced hepatoprotective activity in liver. In rats injected with cadmium chloride, the activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), γ-glutamyl transferase (GGT) was significantly (p < 0.05) increased when compared to those values in control rats. The rats administrated with P. daemia extract and cadmium chloride showed a significantly (p < 0.05) decreased levels of serum AST, ALP, LDH and GGT. This study suggested that P. daemia may be implicated as a hepatoprotective agent for therapeutic purposes.Keywords
Cadmium Chloride, Hepatoprotective Activity, Pergularia daemia.
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