Research Journal of Pharmacognosy and Phytochemistry

Abstract

Hepato- toxicity is a common toxicity happening during the treatment of chronic disease like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region has laxative , sedative, anticancer property and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also posses hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against paracetamol induced hepatotoxicity in albino rats. The extract when evaluated at dose of 100mg/ kg was found to significantly reduce the elevated levels of serum lysosomal enzyme Sgpt, Sgot, Alp and Bilirubin when compared with standard silymarin.

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