A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Patil, V. R.
- Phytochemical and Toxicological Evaluation of Acorus calamus and Argyreia speciosa Leaves Extract
Authors
1 Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune-411 033, Maharashtra, IN
2 Tapi Valley Education Society's, Hon. Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur Dist: Jalgaon-425 503, Maharashtra, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 8, No 3 (2016), Pagination: 121-124Abstract
In present study Acorus calamus and Argyreia speciosa were collected, their authentications were performed. These two plants were extracted by three different solvents. Extracts of these plants were subjected to different phytochemical analysis. Acute toxicity studies of these plant extracts were performed to determine their safety. Phytochemical Investigation were carried out by performing various tests viz. test for detection of carbohydrate, alkaloid, proteins, volatile oils, flavonoids, saponins, phenols, resins, tannins, amino acid, steroids, triterpenoids, anthraquinones and coumarines. Acute oral toxicity was performed using OECD 420 guidelines. Groups of female rats are dosed in a stepwise procedure using the fixed doses of 5, 50, 300 and 2000 mg/kg. No toxic symptoms or mortality were observed in any animals, which lived up to 14 days after the administration of all extract of AC and AS upto the level of 2000 mg/kg body weight.Keywords
Acorus calamus, Argyreia speciosa, Phytochemical, Toxicological.
- Effect of Arogyavardhini in Experimental Prostatic Hyperplasia and Inflammation in Rats
Authors
1 Plot no 430, Sector No 28, Nigdi Pradhikaran, Pune, Maharashtra, Pin 411044, IN
2 PDEA’s Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra, IN
3 TVES’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, IN
4 Rajgad Dyanpeeth’s College of Pharmacy, Bhor, Pune, Maharashtra, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 4, No 6 (2012), Pagination: 314-317Abstract
Arogyavardhini, an Ayurvedic herbomineral formulation, was studied for its effect in experimental prostatic hyperplasia induced by testosterone injection s.c for 21 days in rats and inflammation induced in rat hind paw by carrageenan injection s.c. The results showed that Arogyavardhini at dosage of 100, 200 and 400 mg/kg orally for 21 days showed significant reduction of prostatic hyperplasia as indicated by decreased prostate weight and volume and hispathological observations. It also significantly inhibited carrageenan induced hind paw oedema in dose dependant manner. These results suggest that Arogyavardhini is effective in prostate disorder like Benign Prostatic Hyperplasia (BPH) by inhibiting proliferative and inflammatory mechanisms in prostate.