Research Journal of Pharmacognosy and Phytochemistry

Shivani Watak ¹, Swati S. Patil ¹

Affiliations
1 Prin. K.M. Kundnani College of Pharmacy, Cuffe Parade, Colaba, Mumbai, IN

Abstract

Phenolic compounds are metal chelator, it is interesting to investigate Their metal-chelating property, which stimulates our interest to evaluate Zn(II)- chelating ability and the effect of Zn(II) on its radical-scavenging activity by theoretical calculation. It was revealed that Phenolic compound could efficiently sequester Zn(II) and the Zn(II)-Phenolic compound complexes were more active than the parent compound in scavenging radicals by donating proton or electron. Therefore, Phenolic compounds are a multipotent agent, with the activities of scavenging ROS, blocking A aggregation and chelating metal ions.

Keywords

Metal Chelator, Antioxidant, Phenolic Compounds.

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