Research Journal of Pharmacognosy and Phytochemistry

Ashok Kumar Tiwari ¹, Neelesh Dwivedi ¹, Manoj Kumar Tripathi ¹, Aakanksha Tiwari ¹, Pawan Kumar Ahirwar ¹, Sharda Prasad Tripathi ¹

Affiliations
1 Ayurveda Sadan, Arogyadham, JRD Tata Foundation for Research in Ayurveda and Yoga Sciences, Deendayal Research Institute, Chitrakoot, Satna, Madhya Pradesh-485334, IN

Abstract

Ayurvedic medicine Kutajastaka Pravahi Kvatha, known to be effective in Daha (burning sensation); Raktatisara (Diarrhoea with blood); Sula (pain); Amadosa; (products of impaired digestion and metabolism) and Sarvatisara (all types of diarrhoea), has been standardized by following modern scientific quality control procedures for the finished product. The results of physico-chemical parameters viz. specific gravity (1.01), total solids (4.45%) and pH (4.50) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopiea of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Kutajastaka Pravahi Kvatha facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in understanding the underlying mechanism of pharmacological action.

Keywords

Standardization, Ayurvedic Formulation, Kutajastaka Pravahi Kvatha, Pharmacopoeial Standards.

Full Text

     

Ashok Kumar Tiwari ¹, Neelesh Dwivedi ¹, Manoj Kumar Tripathi ¹, Sharda Prasad Tripathi ¹

Affiliations
1 Ayurveda Sadan, Arogyadham, JRD Tata Foundation for Research in Ayurveda and Yoga Sciences, Deendayal Research Institute, Chitrakoot, Satna, Madhya Pradesh-485334, IN

Abstract

The present study deals with the quality control of the Ayurvedic formulation Darvyadi Kvatha Ghana Vati (Tablet) following quality control procedures for the finished product. The results of physico-chemical parameters viz. loss on drying (9.7 %), average weight (5.0 %), friability (0.15 %) and disintegration time (85 min) were found. Microbiological limit test and heavy metals Pb, Cd, As, Hg were also found within the limits set by Ayurvedic Pharmacopeia of India (API). The obtained values can be adapted to lay down new pharmacopoeial standards with batch to batch consistency. The phytochemical constituents found in the raw material used for the preparation of Darvyadi Kvatha Ghana Vati (Tablet) facilitate the desirable therapeutic efficacy of the medicinal formulations a whole in elements and also could help in knowing the underlying mechanism of pharmacological action.

Keywords

Ayurvedic Formulation, Darvyadi Kvatha Ghana Vati, Quality Control.

Full Text