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Authors
Affiliations
1 Chitkara College of Pharmacy, Chandigarh Patiala National Highway, Rajpura-140401, Patiala, Punjab, IN
2 Chitkara College of Pharmacy, Rajpura, Patiala-140401, Punjab, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 41-45
Abstract
Medical plants play an important role in the management of diabetes mellitus especially in developing countries where resources are meager. Plant-based drugs have been used against various diseases since a long time. The nature has provided abundant plant wealth for all the living creatures, which possess medicinal virtues. Therefore, there is a necessity to explore their uses and to conduct pharmacognostic and pharmacological studies to ascertain their therapeutic properties. In fact, nowadays, diabetes is a global problem. Hence, the present study aims to open new avenues for the improvement of medicinal uses of Verbesina encelioides Benth. ischolar_mains for the selected area for diabetes.. Dried aqueous and alcoholic extracts were subjected for hypoglycaemic activity in swiss albino mice (30-40g). Blood sugar level was determined using digital glucometer. The oral administration of ischolar_mains extracts at doses of 400 mg/ kg lead to a significant blood glucose reduction in normal and in Streptozotocin, alloxan diabetic mices significantly within 4 h. Continued, daily administration of the drug produced a sustained effect.
Keywords
Verbesina encelioides, Alloxan-Induced Diabetes, Streptozotocin-Induced Diabetes, Hypoglycaemic Activity.
