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Authors
Affiliations
1 JKK Muniraja Medical Research Foundation College of Pharmacy, B-Komarapalayam-638 183, IN
2 Department of Pharmaceutical Chemistry, JKKMMRF College of Pharmacy, Ethirmedu, Komarapalayam 638183, Namakkal Dt, Tamilnadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 5 (2010), Pagination: 421-424
Abstract
The methanol extract of aerial part of Clerodendrum inerme were investigated for anti-inflammatory and analgesic at the dose 200 mg/kg, body weight. The experimental paradigms used were carrageenan, induced pedal edema for anti-inflammatory activity, acetic acid induced writhing methods were used to assess analgesic activity. In acute phase inflammation, a maximum inhibition 60.17% (P < 0.01) was noted at the dose of 200 mg/kg after 3 h of treatment with methanol extract of Clerodendrum inerme (MECI) in carrageenan, induced pedal edema respectively. The extract also produced significant (P < 0.01) analgesic activity in both paradigms. This study exhibits that the methanol extracts of aerial part of Clerodendrum inerme possess anti-inflammatory and analgesic activities.
Keywords
Clerodendrum inerme, Anti-Inflammatory, Analgesic.
