A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Patel, P. M.
- Pharmacognostic and Phytochemical Study of Oleo Gum Resin from Boswellia serrata
Authors
1 Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan – 3, IN
2 Department of Pharmaceutical Analysis, Shree B.M Shah College of Pharmaceutical Education and Research, Modasa, Gujarat, 383315, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 5, No 5 (2013), Pagination: 244-250Abstract
Aim of the study: Pharmacognostic and Phytochemical evaluation of oleogum resin of Boswellia serrata Roxb (Burseraceae) is valuable consideration for the recognition as well as excellence purpose.
Materials and Methods: The pharmacognostic evaluation of the plant included morphology and microscopy of the oleo gum resin, leaf and bark. The phytochemical screening of the oleo gum resin of the plants was carried out by successive extraction. Thin layer chromatography and high performance thin layer chromatography method were performed for the identification of chemical constituents present in the oleo gum resins.
Results: Results of the present study revealed that the leaves as well as bark of Boswellia serrata were evaluated morphologically and microscopically. Microscopy of leaf and bark shows the characters of dicotyledonous plants Boswellia serrata. Phytochemical screening parameters were established from the oleo gum resin of the plant. TLC of the isolated boswellic acids were performed for the identification. The Rf values obtained in TLC plate was indicated the presence of different types of the boswellic acids which is match with standard Rf values.
Conclusion: From the present study, the Pharmacognostical analysis of plant Boswellia serrata confirms the authenticity of the plant. Examination of TLC confirmed the presence of different types of boswellic acids. The examination of isolated boswellic acids through HPTLC showed four peaks which give the identity of four types of boswellic acids.
Keywords
Boswellia serrata, Boswellic Acids, Pharmacognostic Study, Phytochemical Screening.
- Anticonvulsant Activity of Boswellic Acids against Maximal Electroshock- Induced Convulsive Rats and Picrotoxin-Induced Convulsive Mice
Authors
1 Gayatree Automobiles, N/R Jalaram Garage, Vrundavan Park, Mandvi Bhuj Highway, Mandvi, Kutch, 370465 Gujarat, IN
2 Department of Pharmaceutical Analysis, Shree B.M Shah College of Pharmaceutical Education & Research, Modasa, Gujarat, 383315, IN
3 Veerayatan Institute of Pharmacy, Jakhania, Bhuj- Mandvi Road, Mandvi, Kutch Gujarat, 370460, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 4, No 6 (2012), Pagination: 318-321Abstract
Aim of the study: Epilepsy the most serious brain disorder is characterized by recurrence of seizures. So, the present study was carried out on rats and mice to evaluate the anticonvulsant activity of boswellic acids (BA) isolated from oleo-gum resin of Boswellia serrata Roxb (Burseraceae).
Materials and Methods: Three different doses of BA viz., 50, 100 and 200 mg/kg, were studied against the maximal electroshock seizure (MES) and picrotoxin (PCT)-induced convulsions. Phenytoin sodium (PS) and diazepam (DZ) were used as reference standard in MES-induced convulsion model and PCT-induced convulsions respectively.
Results: Results of the present study revealed that BA showed dosedependent anticonvulsant activity by significantly decreasing the duration of hind limb tonic extension (HLTE) and by increasing the latency of HLTE as compared to control (p<0.001) in MES model. The BA did not show any significant anticonvulsant activity in PCT-induced convulsion model.
Conclusion: From the present study, it is concluded that the BA possesses anticonvulsant activity against electrically induced convulsions in experimental animals, which supports the ethno medicinal claim of the plant in the management of epilepsy.