Research Journal of Pharmacognosy and Phytochemistry

H. S. Chandel ¹, A. Pathak ², Mukul Tailang ³

Affiliations
1 Truba Institute of Pharmacy- Bhopal (M.P), IN
2 Department of Pharmacy, Barkatullah University- Bhopal(M.P), IN
3 Department of Drug Technology, Derna, LY

Abstract

Herbal medicines have played a vital role in the therapeutics when safe and efficient therapy is required. Herbs had been used by all cultures throughout history but India has one of the oldest, richest and most diverse cultural living traditions associated with the use of medicinal plants. Presently the need for herbal drugs is growing because of the fact that these are biosafe with no side effects. Many analysis-based studies regarding pharmacological research in India, have been conducted in the past. Pharmaceutical research across the world shows that, natural products are potential sources of novel molecules for drug development.

Diabetes is the world's largest endocrine disease involving metabolic disorder of carbohydrate, fat and protein. According to the WHO projections, the prevalence of diabetes is likely to increase by 35%. Statistical projections about India suggest that the number of diabetics will rise from 15 million in 1995 to 57 million in the year of 2025 making it the country with the highest number of diabetics in the world. In this work a polyherbal formulation was developed and compared with that of a marketed formulation.

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Sonali Khare ¹, Mukul Tailang ², Amrish Sharma ², Tripti Shukla ²

Affiliations
1 People’s Hospital, PCMS Campus, HIG C-4, Bhanpur Road, Bhopal-462 037 (M.P), IN
2 People’s Institute of Pharmacy and Research Centre, Bhopal Bhanpur Road, Bhopal-462 037 (M.P.), IN

Abstract

Diabetes mellitus is a metabolic disorder and associated with many other metabolic functional alterations. The bark of Ficus bengalensis and other plants are reported as antidiabeticand hypolipidemic due to presence of flavonoids and sterols. Based on literature survey, tribal information and chemical constituents, the present study is undertaken to observe the hypolipidemic potential of leaves and fruits of Ficus bengalensis because they also contain the same active constituents. Hence, the leaves and fruits may have same activity like bark. To study the object, different doses of ethanolic extract of leaves and fruits of Ficus bengalensis was given to alloxan induced diabetic rats.

Keywords

Ficus bengalensis, Hypolipidemic, Antidiabetic, Alloxan, Flavonoids, Sterol.

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