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Authors
Affiliations
1 Nalanda College of Pharmacy, Nalgonda, A.P, IN
2 Department of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda-508001 Andhra Pradesh, IN
3 ASN Pharmacy College, Tenali, A.P, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 1 (2010), Pagination: 67-69
Abstract
There has always been a closed association between plants and human beings through ancient time and till date. Physalis angulata is an annual herb indigenous to many parts of the tropics, including the Amazon. It can be found on most continents in the tropics, including Africa, Asia, and the Americas. It grows up to 1 m high, bears small, cream-colored flowers, and produces small, light yellowish-orange, edible fruit sometimes referred to as Cutleaf Groundcherry. It is a popular medicine used due to its anti inflammatory effects, anti tumor effects, immunomodulatory effects etc. The present study is to evaluate the anti bacterial and anti platelet activity of the ethanolic leaf extract of Physalis angulata. From the phytochemical screening it was found that the plant is mainly constituted with phenols, steroids and flavonoids .The anti bacterial activity was performed by well diffusion method on various concentrations of the extract. Gentamycin was used as the standard and ethanol as the control. In the antiplatelet activity study, the platelet was induced using adenosine di phosphate. Nephlometer was used to observe the aggregation. It was observed that the ethanolic leaf extract showed pronounced anti platelet activity. But the anti bacterial activity was found to be false positive.
Keywords
Physalis angulata, Anti-Platelet, Anti Bacterial, Nephlometer.
