Research Journal of Pharmacognosy and Phytochemistry

F. Nikhat ¹, D. Satyanarayana ², D. K. Suresh ², M. G. Purohit ², H. Raza ², S. M. Hamza ²

Affiliations
1 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, IN
2 Department of Pharmaceutical Chemistry, Luqman College of Pharmacy, Gulbarga-585201, IN

Abstract

The present study was carried out to investigate the analgesic activity of the prepared formulation 50mg/kg and 200mg/kg body weight in the form of gel on albino rats by Tail immersion method. The different dose level of prepared gel was applied to the rat according to the body weight to the tail which is marked at 5cm and was subjected to analgesic activity. The significance analgesic activity is observed after 1_/2 hr of the application which was compared with standard dichlofenac gel, the activity decreased after 2 hr of the application. The gel was prepared from the isolated constituents of syzygium cuminii (L) skeel ischolar_main extract. The aim of the work is to prepare such a formulation which is having natural analgesic activity. The expected result from the formulation was obtained for first time. The further work is going on in our laboratory.

Keywords

Analgesic, Dichlofenac Gel, Formulation, Constituents.

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F. Nikhat ¹, D. Satyanarayana ¹, E. V. S. Subhramanyam ¹

Affiliations
1 Department of Pharmaceutical Chemistry, Nitte Gulabi Shetty Memorial Institute of Pharmaceutical Sciences, Mangalore-574160 Karnataka, IN

Abstract

The object of this review is to highlight the importance of multipurpose indigenous plant Zizyphus mauritiana Lamk Belonging to the family Rhamnaceae . It has been used for centuries as folk remedy in India to treat different disease such as antidiabetic, antioxidant, anti-inflammatory and neurological disorders such as sedative hypnotics, overine complication. It contain several constituent belonging to category alkaloide, Glycoside , flavanoids, triterpinoides, steroids and fruit pulp contain important nutrients . There are five reports are available on the clinical uses of this plant. Indeed the purpose is to outline the Research student to explore the Phytochemistry and pharmacology of indigenous system of medicine. This was a simple tribute to focus on the economical importance of Indian medicinal plants.

Keywords

Zizyphus mauritiana Lamk, Rhamunaceae, Antidiabetic, Antioxidant, Anti-Inflammatory, Alkaloids, Glycoside, Flavanoids, Triterpinoides, Steroids.

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