Research Journal of Pharmacognosy and Phytochemistry

Ajay Kumar Meena ¹, Brijendra Singh ², Vijay Simha ², V. Gautam ², M. M. Rao ¹

Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala - 147001 (Punjab), IN
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, IN

Abstract

Ashwagandha is a reputed drug mentioned in the ancient books of Ayurveda and Siddha for the treatment of stress, hypertension, rejuvenative, sound sleep, brain functions and reducing the high cholesterol levels. It is a stout shrub that reaches a height of 170 cm (5.6 ft). For the standardization of this drug Physico-chemical and Phyto-chemical parameters were carried out such as moisture content, ash values, pH values, extractability in water and alcohol were carried out. Thin Layer Chromatography studies were also carried out to ascertain the quality of this drug. The present study summarizes the difference in two places of Withania somnifera Dunal. This study also helps to identify the right place for cultivation of medicinal plants and quality assessment.

Keywords

Withania somnifera Dunal, Ayurveda, Physicochemical, Standardization, Quality.

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A. K. Meena ¹, Uttam S. Niranjan ², A. K. Yadav ², Brijendra Singh ², A. K. Nagaria ², A. Gaurav ², M. M. Rao ³

Affiliations
1 National Institute of Ayurvedic Pharmaceutical Research, Patiala-147001, Punjab, IN
2 School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, IN
3 National Institute of Ayurvedic Pharmaceutical Research, Patiala –147001, Punjab, IN

Abstract

Vitex negundo Linn. is an large shrubs or small trees which is used in several traditional medicines to cure various diseases. This shrub has been known to posses hepatoprotective, antioxidant, anti-inflammatory, analgesic and antifungal activity. A wide range of chemical compounds including polyphenolic, terpenoids , glycosidic iridoids and alkaloids are present in this shrubs. Vitegnoside, negundoside, agunside, 5,3- dihydroxy-7,8,4-trimethoxy flavanone, 7,8-dimethyl herbacetin 3- rhamnoside etc. have been isolated from this plant. The presented review summarizes the information concerning the botany, ethnopharmacology, phytpchemistry, biological activity and toxicity of the Vitex negundo shrubs.

Keywords

Vitex negundo Linn, Antioxidant, Phytpchemistry, Antiinflammatory, Toxicity.

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