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Kale, A. P.
- Effect of Arogyavardhini in Experimental Prostatic Hyperplasia and Inflammation in Rats
Authors
1 Plot no 430, Sector No 28, Nigdi Pradhikaran, Pune, Maharashtra, Pin 411044, IN
2 PDEA’s Seth Govind Raghunath Sable College of Pharmacy, Saswad, Pune, Maharashtra, IN
3 TVES’s Loksevak Madhukarrao Chaudhari College of Pharmacy, Faizpur, Maharashtra, IN
4 Rajgad Dyanpeeth’s College of Pharmacy, Bhor, Pune, Maharashtra, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 4, No 6 (2012), Pagination: 314-317Abstract
Arogyavardhini, an Ayurvedic herbomineral formulation, was studied for its effect in experimental prostatic hyperplasia induced by testosterone injection s.c for 21 days in rats and inflammation induced in rat hind paw by carrageenan injection s.c. The results showed that Arogyavardhini at dosage of 100, 200 and 400 mg/kg orally for 21 days showed significant reduction of prostatic hyperplasia as indicated by decreased prostate weight and volume and hispathological observations. It also significantly inhibited carrageenan induced hind paw oedema in dose dependant manner. These results suggest that Arogyavardhini is effective in prostate disorder like Benign Prostatic Hyperplasia (BPH) by inhibiting proliferative and inflammatory mechanisms in prostate.