Refine your search
Collections
Co-Authors
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Nagpal, Manju
- Gastroretentive Drug Delivery Systems: A Promising Approach
Abstract Views :179 |
PDF Views:0
Authors
Yashomita Mehta
1,
Sunita Nirban
2,
Sunil Kumar
2,
Kuldeep Malodia
2,
Pankaj Rakha
3,
Manju Nagpal
2
Affiliations
1 Lord Shiva College of Pharmacy, Sirsa, IN
2 Lord Shiva College of Pharmacy, Sirsa, IN
3 Rajendra Institute of Technology and Sciences, 4th mile stone, Hisar Road, Sirsa, IN
1 Lord Shiva College of Pharmacy, Sirsa, IN
2 Lord Shiva College of Pharmacy, Sirsa, IN
3 Rajendra Institute of Technology and Sciences, 4th mile stone, Hisar Road, Sirsa, IN
Source
Research Journal of Pharmaceutical Dosage Form and Technology, Vol 3, No 1 (2011), Pagination: 1-6Abstract
Controlled release drug delivery system (CRDDS) have been most extensively used to improve therapy of certain drugs, but several physiological difficulties faced with CRDDS is the inability to restrain and remain in the gastric region for several hours which limit the bioavailability of drug. Hence drug delivery systems with prolonged gastric residence time (GRT) are an approach to improve bioavailability of drugs, reduction in dose thereby leading to less side/toxic effects. Many approaches have been utilized in the development of gastric retention drug delivery systems (GRDDS) such as floating system, extended system, high density system, superporus system, bioadhesive system, and magnetic system etc. This review also summarizes the in vitro and in vivo studies to evaluate the performance and application of GRDDS. These systems are useful to several problems encountered during the development of a pharmaceutical dosage form.Keywords
Gastric Retention, Effervescent, Floating, Magnetic.- Comparison of Biorelevant and Compendial Dissolution Media and Prediction of In-vivo Plasma Profile of BCS Class II Drug
Abstract Views :220 |
PDF Views:0
Authors
Affiliations
1 Rajendra Institute of Tech. and Sciences, Sirsa, Haryana, IN
2 Rajendra Institute of Tech. and Sciences, Sirsa, Haryana, IN
3 NCRD’s Sterling Institute of Pharmacy, Navi Mumbai, IN
4 Glaxosmithcline Pvt. Ltd., Mumbai,, IN
1 Rajendra Institute of Tech. and Sciences, Sirsa, Haryana, IN
2 Rajendra Institute of Tech. and Sciences, Sirsa, Haryana, IN
3 NCRD’s Sterling Institute of Pharmacy, Navi Mumbai, IN
4 Glaxosmithcline Pvt. Ltd., Mumbai,, IN