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Men, Qiu-Lei
- Chronic Toxic Effect of Lead on Male Testis Tissue in Adult Pelophylax nigromaculata
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1 College of Life Sciences, Anqing Normal University, Anqing 246011, Anhui, CN
1 College of Life Sciences, Anqing Normal University, Anqing 246011, Anhui, CN
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Nature Environment and Pollution Technology, Vol 16, No 1 (2017), Pagination: 213-218Abstract
Lead (Pb) is one of the most common heavy metals in nature which has an adverse effect on aquatic ecosystems and affects animal health. Animal survival depends on its reproductive ability. To analyse the influence of Pb on the male testis tissues in the spot frog (Pelophylax nigromaculata), the male adult individuals were exposed to Pb (10, 100 and 1000 μg/L) in water for 30 days. We observed the spermatic histopathologic structure and detected the expression and location of androgen receptors (AR) on the germ cells by immunohistochemical method. Compared to the control, the testis histopathologic structure and the expression of AR at Pb treatment were different. At relatively higher concentration (100 and 1000 μg/L), the changes of spermatic pathological mainly included germ cell necrosis, congestion and fibrosis congestion. The expressions of AR on the gonad cells were affected by Pb. With the increase of Pb concentration, AR expressions were decreased.Keywords
Lead, Testis, Pelophylax nigromaculata, Androgen Receptor.Full Text
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