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Chaudhari, Sandip T.
- Clinical Profile of End Stage Renal Disease in Patients Undergoing Hemodialysis
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PDF Views:77
Authors
Affiliations
1 Department of General Medicine, Dr. Vasantrao Pawar Medical College and Research Centre, Nashik - 422207, Maharashtra, IN
1 Department of General Medicine, Dr. Vasantrao Pawar Medical College and Research Centre, Nashik - 422207, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 4, No 1 (2017), Pagination: 8-13Abstract
Context: Chronic kidney disease is an increasing health problem worldwide and in its final stage (stage V) can only be treated by renal replacement therapy, mostly hemodialysis. Hemodialysis has a major influence on the everyday life of patients and many patients report dissatisfaction with treatment. Objectives: To study the clinical profile of patients with ESRD undergoing hemodialysis and to find out possible etiology which may have led to ESRD in these patients? Settings and Design: This is a prospective, observational study carried out in a tertiary care hospital. Methods and Material: 50 patients, older than 15 years who were on maintenance hemodialysis in this hospital on outpatient basis for more than 3 months were selected for the study. Detailed clinical history, general and systemic examination of all patients was performed. Two manifestations pertaining to each system was taken for study. Statistical Analysis Used: Descriptive as well as inferential statistics were used to analyze the data. Results: Most patients were in the age group of 51-60 with male: female ratio of 1.77:1. Diabetes and hypertension were most common causes for ESRD. Anemia and electrolyte disturbances like hyperkalemia along with hypocalcemia, hyperphosphatemia and hyperuricemia have common associations with ESRD. Conclusions: Lack of health awareness and lack of regular health checkup in general population is one of the culprit factor for progression of renal disease. Health awareness in general population may decrease the incidence of ESRD or postpone the development of ESRD.Keywords
Chronic Kidney Disease (CKD), End Stage Renal Disease (ESRD).Full Text
References
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- The Correlation of Hyponatremia with Neurological Features in Adult Patients Admitted in an ICU Setting in a Tertiary Care Centre
Abstract Views :195 |
PDF Views:92
Authors
Affiliations
1 Former PG Resident, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
2 Associate Professor, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
3 Professor, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
1 Former PG Resident, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
2 Associate Professor, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
3 Professor, Department of General Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik - 422003, Maharashtra, IN
Source
MVP Journal of Medical Sciences, Vol 7, No 1 (2020), Pagination: 113-122Abstract
Background: Hyponatremia is the most prevalent electrolyte abnormality worldwide, presenting at even higher rates in the ICU setting. It is one of the leading causes of metabolic encephalopathy and can present with a myriad of neurological features. It is defined by a serum sodium level <135 mEq/L. The present study is designed to evaluate the neurological symptoms in a patient with hyponatremia and to correlate them with the degree of hyponatremia. Aims and Objectives: 1) To study the neurological manifestations in ICU patients found to have hyponatremia 2) To study the correlation between neurological manifestations and serum sodium level. Materials and Methods: This is Prospective Observational study of 2 years duration in which 90 patients were studied with the following criteria: Age ≥18 years, either sex admitted in the ICU having sodium Level of < 135 mMol/L on admission. A thorough neurological examination including Mini Mental Status Examination (MMSE) and Glasgow Coma Scale (GCS) was done at presentation. The data was then analyzed. Results: There was a male predominance (64.44%) amongst the study population. Most patients belonged to the age group of 51-60 years (73.3%) followed by > 60 years (31.1%). Disorientation (41.11%) was the most common neurological features followed by drowsiness (31.11%).Maximum number (48.7%) of patients having mild hyponatremia were asymptomatic. At presentation, most had a normal Mini Mental Status Examination (MMSE) score (28.89%) followed by moderate cognitive impairment (27.78%), GCS scores ≥13 was seen in 56.67% population followed by GCS 9-12 (41.11 %). 2 (2.2%) patients succumbed in the study population. Conclusion: Hyponatremia is a common electrolyte abnormality causing significant morbidity and mortality, especially in the older age group. It is one of the leading causes of metabolic encephalopathy. As it can be asymptomatic in the initial stages, and is treatable, it should evaluated in all patients with subtle as well as overt neurological signs to prevent further neurological deterioration. MMSE scoring is a useful tool for neurological assessment in hyponatremia.
Keywords
Hyponatremia, Neurological Features, GCS, MMSEFull Text
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