S. D. Chavhan ¹, S. V. Mahajan ¹, A. J. Vankudre ²

Affiliations
1 Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik, IN
2 Department of Community Medicine, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik, IN

Abstract

Background: Papulosquamous lesions of the skin are encountered with considerable frequency. There is overlap of both clinical pattern and distribution of papulosquamous skin disorders, which often makes clinical diagnosis difficult. However, some of the histopathological features are specific and characteristic for each entity. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis. Material & Methods: A cross sectional study was done in department of pathology in which after satisfying inclusion criteria all papulosquamous lesion patients irrespective of age & gender were included in study in defined period. A brief history and dermatological examination was carried out. Skin biopsies taken were fixed in 10% formalin and subjected for tissue processing. The processed tissue was embedded in paraffin to obtain five-micron thin sections. The sections were stained with routine hematoxylin and eosin stain, followed by microscopic examination. Result: Out of 61 patients of papulosquamous lesion most common diagnosis was Lichen planus, (57.37 %) followed by Psoriasis (32.78 %). Commonest age group reporting Lichen planus & Psoriasis was 21–40 yrs. Male preponderance was noted in all papulosquamous lesion patients. Histological features commonly seen were hyperkeratosis, parakeratosis in both Lichen planus & Psoriasis patients.

Keywords

Papulosquamous, Clinical, Histologiscal, Histological Features

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P. Fotedar ¹, S. S. Rairikar ¹, A. J. Vankudre ¹, S. V. Mahajan ¹

Affiliations
1 Department of Pathology, Dr. Vasantrao Pawar Medical College, Nashik, IN

Abstract

Introduction & Aim: To study variation of haematological parameters in different species of malaria with special reference to the total leucocyte and platelet count. Methods: This study was conducted in a Tertiary Health Care Centre, from June 2010 to June 2012. All positive cases of malaria proved on peripheral blood smear in both IPD and OPD patients were included in our study and all cases negative for malaria were excluded. Results: During this study, 119 positive cases of malaria were found in all OPD and IPD patients. In these, 74 cases (62.2%) were of Plasmodium vivax, 35 cases (29.4%) were mixed infections and 10 cases (8.4%) were of Plasmodium falciparum. Amongst the positive cases the ring forms of Plasmodium vivax, mixed infection & Plasmodium falciparum were 56(47.1%), 35(29.4%) and 4(3.4%) respectively. Out of the 109 pure vivax and mixed infection cases, the number of cases showing amoeboid forms were 14(11.8%). Cases of immature schizont were 75(63%) and mature schizont were 17(14.3%). The gametocytes of Plasmodium vivax, mixed infections & Plasmodium falciparum in our study were 5(17.9%), 2(7.1%) and 21(75%) respectively. Mean & Median platelet count in our study was 1,05,075/cumm & 90,000/cumm respectively. The mean platelet count was found significantly lower in cases of P. vivax having gametocyte compared to P. falciparum with gametocyte. Higher parasitic index was associated with lower platelet count.

Keywords

Haematological Parameters, Malaria, Parasitemia

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