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A Study of Correlation between Type 2 Diabetes Mellitus and Glycosylated Haemoglobin in a Tertiary Care Centre


Affiliations
1 Associate Professor, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
2 Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
3 Professor and Head, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, India
 

Background: Diabetes is a silent killer. Looking at the alarming presence of diabetes and its morbidity and mortality in India, we need to diagnose this metabolic disorder accurately and at the earliest. We have carried out this study to determine correlation of fasting blood glucose, post meal blood glucose and glycosylated haemoglobin in type 2 Diabetes Mellitus and to find the cut off value of glycosylated haemoglobin to diagnose type 2 diabetes mellitus. Materials and Methods: A cross sectional study was carried out among 298 cases of type 2 Diabetes Mellitus attending a tertiary care centre in Maharashtra during August 2018 to August 2020. Results and Conclusions: Majority were males and in the age group of 41 to 50 years. Fasting Blood Glucose (FBS) and Postprandial Blood Glucose (PPBS) are strongly correlated to Glycosylated Haemoglobin (HbA1c). Association between FBS and PPBS is statistically significant. Correlation of PPBS and HbA1c is stronger than that of FBS and HbA1c. Cut off level of HbA1c is higher in the study subjects in comparison to standard cut off value of 6.5%.

Keywords

Fasting Blood Glucose, Glycosylated Haemoglobin, Postprandial Blood Glucose, Type 2 Diabetes Mellitus
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  • A Study of Correlation between Type 2 Diabetes Mellitus and Glycosylated Haemoglobin in a Tertiary Care Centre

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Authors

Devangana M. Rajyaguru
Associate Professor, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
Anupama R. Kolte
Former PG Resident, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
Preeti Bajaj
Professor and Head, Department of Pathology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, India

Abstract


Background: Diabetes is a silent killer. Looking at the alarming presence of diabetes and its morbidity and mortality in India, we need to diagnose this metabolic disorder accurately and at the earliest. We have carried out this study to determine correlation of fasting blood glucose, post meal blood glucose and glycosylated haemoglobin in type 2 Diabetes Mellitus and to find the cut off value of glycosylated haemoglobin to diagnose type 2 diabetes mellitus. Materials and Methods: A cross sectional study was carried out among 298 cases of type 2 Diabetes Mellitus attending a tertiary care centre in Maharashtra during August 2018 to August 2020. Results and Conclusions: Majority were males and in the age group of 41 to 50 years. Fasting Blood Glucose (FBS) and Postprandial Blood Glucose (PPBS) are strongly correlated to Glycosylated Haemoglobin (HbA1c). Association between FBS and PPBS is statistically significant. Correlation of PPBS and HbA1c is stronger than that of FBS and HbA1c. Cut off level of HbA1c is higher in the study subjects in comparison to standard cut off value of 6.5%.

Keywords


Fasting Blood Glucose, Glycosylated Haemoglobin, Postprandial Blood Glucose, Type 2 Diabetes Mellitus

References