MVP Journal of Medical Sciences

Open Access Open Access  Restricted Access Subscription Access

An Observational Study of Dermatological Manifestations in Patients of Chronic Renal Failure Undergoing Hemodialysis


Affiliations
1 PG Resident, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422002, Maharashtra, India
2 Associate Professor, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
3 Professor and Head, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
4 Senior Resident, Department of Dermatology, Venerology and Leprology, Dr. Vasantrao Pawar Institute of Medical Sciences and Research, Nashik – 422003, Maharashtra, India
 

Background: Chronic Renal Failure (CRF) patients develop myriad of cutaneous findings. Novel cutaneous changes are being described since the introduction of hemodialysis, which prolongs the life expectancy, and thus more time for the skin changes to develop. Aims & Objectives: We aimed to evaluate the prevalence of dermatologic manifestations among the patients suffering from Chronic Renal Failure (CRF) who are on hemodialysis. Methods: 93 patients with CRF receiving hemodialysis were evaluated for skin, hair and nail changes. Results: All the enrolled patients experienced some skin problem. The most prevalent cutaneous manifestation was xerosis (54.8%), followed by pallor (21.5%), pruritus (19.35%) and dyspigmentation (18.3%). Other dermatologic manifestations included Kyrle’s disease (5.4%); fungal (5.4%), bacterial (6.5%) and viral (3.2%) infections and purpura (9.7%). Recorded nail changes were half and half nail (21%), koilonychia (39.78%), onychomycosis (1.08%), onychorrhexis (6.45%), splinter hemorrhages (1.08%), and Beau’s lines (2%). Hair changes included sparse hair (18.28%), and brittle and lustreless hair (11.83%). Oral cavity manifestations were enlarged tongue with teeth indentations (23.65%). Conclusions: CRF is associated with multiple skin, hair and nail manifestations

Keywords

Dyspigmentation, Koilonychia, Onychomycosis, Pruritus, Xerosis.
Font Size

User
Notifications

  • Udaykumar P, Balasubramanian S, Ramalingam KS, Lakshmi C, Srinivas CR, Mathew AC. Cutaneous manifestations in patients with chronic renal failure on hemodialysis. Indian J Dermatol Venereol and Lepr. 2006; 72:119–25. https://doi.org/10.4103/0378-6323.25636 PMid:16707817

  • Hegab D, Mourad B, Okasha K, Rizk S. Prospective study on prevalence of dermatological changes in patients under hemodialysis in hemodialysis units in Tanta University hospitals, Egypt. Clinical, Cosmetic and Investigational Dermatology. 2014 Nov; 313–17. https://doi.org/10.2147/CCID.S70842 PMid:25419152 PMCid:PMC4235205

  • Thomas R, Kanso A, Sedor JR. Chronic kidney disease and its complications. Prim Care. 2008; 35(2):329–44. https://doi.org/10.1016/j.pop.2008.01.008 PMid:18486718 PMCid:PMC2474786

  • Sorour N, Saudi W, Elmasry A, Sanad E. Prevalence of cutaneous manifestations in chronic renal failure patients on regular hemodialysis: A hospital–based study. Egyptian Journal of Dermatology and Venerology. 2014; 34(1):27 https://doi.org/10.4103/1110-6530.137278

  • Chanda GM, Chintagunta SR, Arakkal G. Dermatological manifestations in chronic renal failure patients with and without hemodialysis: A study at a tertiary care centre. J NTR Univ Health Sci. 2017; 6:8–14

  • Singh G, Verma AK, Singh G, Singh SJ. Cutaneous changes in chronicrenal failure. Indian J Dermatol Venereol and Leprol. 1992; 58:320–22.

  • Sultan MM, Mansour HH, Wahby IM, Houdery AS. Cutaneous manifestations in Egyptian Patients with Chronic Renal Failure on regular hemodialysis. J Egypt Women Dermatol Soc. 2010; 7:49–55.

  • Hajheydari Z, Makhlough. Cutaneous and mucosal manifestations in patients on maintenance hemodialysis: A study of 101 patients in Sari, Iran. Iranian Journal of Kidney diseases. 2008; 2:86–90.

  • Falodun O, Ogunbiyi A, Salako B,George AK. Skin changes in patients with Chronic Renal Failure. Saudi J Kidney Dis Transpl. 2011; 22(2):268272

  • Kolla PK, Desai M, Pathapati RM, Valli BM, Pentyala S, Reddy GM, et al. Cutaneous manifestations in patients with Chronic Kidney Disease on maintenance Hemodialysis. ISRN Dermatology. 2012:1–4. https://doi.org/10.5402/2012/679619 PMid:22830039 PMCid:PMC3398619

  • Khanna D, Singal A, Kalra OP. Comparison of cutaneous manifestations in chronic kidney disease with or without dialysis. Postgrad Med J 2010; 86:641–4. https://doi.org/10.1136/pgmj.2009.095745 PMid:21037238


Abstract Views: 312

PDF Views: 105




  • An Observational Study of Dermatological Manifestations in Patients of Chronic Renal Failure Undergoing Hemodialysis

Abstract Views: 312  |  PDF Views: 105

Authors

Madhur Bharat Kelkar
PG Resident, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422002, Maharashtra, India
Rahul Kote
Associate Professor, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
Anil S. Gugle
Professor and Head, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
Manoj Pawar
Associate Professor, Department of Dermatology, Venereology and Leprology, Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik – 422003, Maharashtra, India
Shrikant Kumawat
Senior Resident, Department of Dermatology, Venerology and Leprology, Dr. Vasantrao Pawar Institute of Medical Sciences and Research, Nashik – 422003, Maharashtra, India

Abstract


Background: Chronic Renal Failure (CRF) patients develop myriad of cutaneous findings. Novel cutaneous changes are being described since the introduction of hemodialysis, which prolongs the life expectancy, and thus more time for the skin changes to develop. Aims & Objectives: We aimed to evaluate the prevalence of dermatologic manifestations among the patients suffering from Chronic Renal Failure (CRF) who are on hemodialysis. Methods: 93 patients with CRF receiving hemodialysis were evaluated for skin, hair and nail changes. Results: All the enrolled patients experienced some skin problem. The most prevalent cutaneous manifestation was xerosis (54.8%), followed by pallor (21.5%), pruritus (19.35%) and dyspigmentation (18.3%). Other dermatologic manifestations included Kyrle’s disease (5.4%); fungal (5.4%), bacterial (6.5%) and viral (3.2%) infections and purpura (9.7%). Recorded nail changes were half and half nail (21%), koilonychia (39.78%), onychomycosis (1.08%), onychorrhexis (6.45%), splinter hemorrhages (1.08%), and Beau’s lines (2%). Hair changes included sparse hair (18.28%), and brittle and lustreless hair (11.83%). Oral cavity manifestations were enlarged tongue with teeth indentations (23.65%). Conclusions: CRF is associated with multiple skin, hair and nail manifestations

Keywords


Dyspigmentation, Koilonychia, Onychomycosis, Pruritus, Xerosis.

References





DOI: https://doi.org/10.18311/mvpjms%2F2019%2Fv6i2%2F22903