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Study of Serum Alkaline Phosphatase Levels among Psoriasis Patients and Comparative Group in Tertiary Care Institute


Affiliations
1 Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India
 

Background: Psoriasis is a chronic relapsing autoimmune skin disease of unknown etiology, characterised by complex alterations in epidermal growth and differentiation. Oxidative stress is a known risk factor for exacerbation of psoriasis. Serum alkaline phosphatase level is a marker of oxidative stress in body. Aims and Objectives: To study and compare serum alkaline phosphatase levels in cases of psoriasis. Materials and Methods: Serum Alkaline Phosphatase levels were evaluated in 100 cases of psoriasis and controls. Results: There was no statistically significant difference between serum alkaline phosphatase levels among cases and controls. Conclusion: Serum alkaline phosphatase levels, as a marker of oxidative stress is not significantly raised in cases of psoriasis.

Keywords

Alkaline Phosphatase, Oxidative Stress, Psoriasis.
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  • Study of Serum Alkaline Phosphatase Levels among Psoriasis Patients and Comparative Group in Tertiary Care Institute

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Authors

Milind D. Deshmukh
Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India
Paresh Shirish Agiwal
Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India
Anil S. Gugle
Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India
Shrikant Kumavat
Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India
Manoj Pawar
Department of Dermatology, Dr. Vasantrao Pawar Medical College Hospital & RC, Nashik – 422003, Maharashtra, India

Abstract


Background: Psoriasis is a chronic relapsing autoimmune skin disease of unknown etiology, characterised by complex alterations in epidermal growth and differentiation. Oxidative stress is a known risk factor for exacerbation of psoriasis. Serum alkaline phosphatase level is a marker of oxidative stress in body. Aims and Objectives: To study and compare serum alkaline phosphatase levels in cases of psoriasis. Materials and Methods: Serum Alkaline Phosphatase levels were evaluated in 100 cases of psoriasis and controls. Results: There was no statistically significant difference between serum alkaline phosphatase levels among cases and controls. Conclusion: Serum alkaline phosphatase levels, as a marker of oxidative stress is not significantly raised in cases of psoriasis.

Keywords


Alkaline Phosphatase, Oxidative Stress, Psoriasis.

References