Journal of Pharmaceutical Research

Abstract

Aim: The primary objective was to study the profile of microvascular complications in newly diagnosed type 2 diabetics in a tertiary hospital and to determine its association with correlates of Metabolic Syndrome.

Settings and Design: This was a prospective observational study conducted over a period of six months among patients attending the Endocrinology outpatient of a tertiary care centre in a South Indian city.

Materials and Methods: We studied the correlation of microvascular complications (neuropathy, nephropathy, retinopathy and foot ulcers) in 44 newly diagnosed type 2 diabetics with associated risk factors i.e., hypertension, obesity and dyslipidemia.

Results: The prevalence of peripheral neuropathy, nephropathy and retinopathy was 15.9%, 2.3% and 2.3% respectively. The study showed that out of 44 patients, 18 had hypertension (40.91%). Four out of the 18 hypertensive patients had microvascular complications (22.2 %). There was a significant association between obesity and peripheral neuropathy (P< 0.05).

Conclusion: There was a maximum prevalence of peripheral neuropathy amongst the newly diagnosed diabetics thus they should be wary of the corresponding symptoms of numbness and tingling of feet. It was seen that out of the total 44 diabetic patients, 9.09% had both hypertension and microvascular complications. The low percentage is because 52% of the total hypertensives were on antihypertensive medication. There was also a significant association between obesity and neuropathy. Thus, those with obesity and hypertension are at a high risk of developing microvascular complications.

Keywords

Full Text

References