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Roy, C.
- Sublethal Toxicity of Malathion Ec 50 on The Biochemical Parameters of Blood in Fejervarya limnocharis
Authors
1 Deptt. of Zoology, G. C. College, Silchar, IN
Source
Indian Science Cruiser, Vol 24, No 4 (2010), Pagination: 45-51Abstract
Paddy fields are inhabited by several species of anuran amphibians. The biochemical changes induced by malathion in F. limnocharis reflect the interferences in various metabolic pathways of anurans of the paddy field. The toxicating impact affected the carbohydrate metabolism at the very outset as revealed by gradual increase in blood sugar level with continuation of exposure in F. limnocharis. F. limnocharis intoxicated with malathion at sub-lethal concentration (0.006 ppm) showed significant increase of blood glucose level from 24 hrs to 96 hrs of exposure ranging from (22.08±0.79) mg/dl to (34.23±0.51) mg/dl as compared to the control value 18.75 ±0.48 mg/dl. Changes in enzyme activity were also employed in the evaluation of toxicological response. Effects of sub-lethal concentrations of malathion (0.006 ppm) was studied on SGOT, SGPT and serum amylase level of F. limnocharis. The study revealed that in different hours of exposure (24 hrs lo 96 hrs) a significant increase in serum glutamate oxalate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT) and serum amylase in comparison with control were observed.Keywords
Biochemical, Physiological, Pollutants, Pathobiological. Carbohydrate, Toxicants, Xenobiotic, Hazardous, Morbidity, Pesticides, Malathion.
- Acute Toxicity of Malathion 50 EC on Fejervarya limnocharis
Authors
1 Deptt. of Zoology, G. C. College, Silchar, IN
Source
Indian Science Cruiser, Vol 26, No 2 (2012), Pagination: 14-22Abstract
Acute toxicity tests were performed on Fejervarya limnocharis with different concentration of malathion 50EC (0.006, 0.008, 0.01, 0. 02, 0.03, 0.04, 0.05, 0.06, 0.07 and 0.08 ppm). On Probit analysis, the Lc50 value estimated for 24 hrs, 48 hrs, 72 hrs, and 96 hrs were 0.07036, 0.04060, 0.02479 and 0.01589 ppm respectively. No marked acute responses were observed in lower doses and in higher doses tremor, convulsion, erratic movement and rapid swimming with ventral side up were observed. Ultimately the test animals sank to the bottom of the jar Abnormal behaviours observed might be due to the inhibition of AchE by the accumulation of acetylcholine causing prolonged excitatory postsynaptic potential.