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Bishayee, Anupam
- Effect of Selenium, Glutathione S-transferase, Glucose-6-phosphate Dehydrogenase and Lipid Peroxidation in Streptozoticin Induced Diabetic Rats
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Authors
Affiliations
1 Division of Biochemistry, Department of Phamaceutical Technology Jadavpur University, IN
2 Division of Biochemistry, Department of Phamaceutical Technology Jadavpur University
1 Division of Biochemistry, Department of Phamaceutical Technology Jadavpur University, IN
2 Division of Biochemistry, Department of Phamaceutical Technology Jadavpur University
Source
Indian Science Cruiser, Vol 6, No 1 (1992), Pagination: 30-32Abstract
Biochemical measurements of specific components of blood, specific enzyme assays and estimation of selenium (Se) content of normal and diabetes induced rats, serve as important indicators of the metabolic state. These help in diagnosing disease and in reigulating treatment. In streptozoticin treated animals there is a tremendous rise in the levels of blood sugar, Se content and also a marked increase in the rates of lipid peroxidation. The activity of the enzyme G-S-transferase was noticeably higher. However G-6-p dehydrogenase activity showed a steady decline.Keywords
Streptozoticin, SelenocysteineReferences
- W H Habig, M J Pahst and W B Jakoby, J Biol Cliem 249, 7130-7139, 1979.