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Authors
Affiliations
1 Dept of Pathology, Emergency Laboratory, Institute of Human Behavior and Allied Sciences (IHBAS), Dilshad Garden, Delhi-110095, IN
2 Institute of Human Behaviour and Allied Sciences (IHBAS), Delhi, IN
Source
The Indian Practitioner, Vol 68, No 1 (2015), Pagination: 46-50
Abstract
Plasma cell leukaemia (PCL) is a rare disorder that can develop spontaneously (primary) or evolve in patients with multiple myeloma (secondary). Histogenetically, plasma cell leukaemia is derived from terminally differentiated B cells. It is diagnosed by the presence of absolute plasma cell count > 2000/ cumm or > 20% circulating plasma cells in blood. We report a rare case of primary plasma cell leukaemia in a patient of bipolar affective disorder presenting with weakness of lower limbs, fatigability, generalized myalgia and mood changes. She was a known case of pulmonary tuberculosis. There was no previous history of multiple myeloma. Clinical spectrum, cytomorphological features and prognosis of PCL are discussed.
Keywords
Primary, Plasma Cell, Leukemia, Multiple Myeloma.
