International Journal of Scientific Engineering and Technology

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Engineered Nanoparticle Aerosol Foam Formulation for Skin Diseases


Affiliations
1 School of Chemical and Biotechnology, SASTRA University, Thanjavur-613401, Tamilnadu, India
2 Sara Industries-ASD, Coimbatore, Tamilnadu, India
 

The objective of the work is to formulate, optimize and evaluate "Itraconazole nanosuspension as aerosol foam formulation" for the treatment of skin diseases such as Cellulitis, Erysipelas, Impeigo and Blastomycosis, Histoplasmosis, Onchomycosis, etc. The solubility of poorly soluble itraconazole can be improved through nanosuspension process and also the absorption rate and bioavailability of drug can be enhanced by means of aerosol foam dispersion at the site of application.

Keywords

Itraconazole, Nanosuspension, Wet Milling, Foam.
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  • Engineered Nanoparticle Aerosol Foam Formulation for Skin Diseases

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Authors

K. Malarvizhi
School of Chemical and Biotechnology, SASTRA University, Thanjavur-613401, Tamilnadu, India
D. Ramya Devi
School of Chemical and Biotechnology, SASTRA University, Thanjavur-613401, Tamilnadu, India
Alfred Raymond
Sara Industries-ASD, Coimbatore, Tamilnadu, India
B. N. Vedha Hari
School of Chemical and Biotechnology, SASTRA University, Thanjavur-613401, Tamilnadu, India

Abstract


The objective of the work is to formulate, optimize and evaluate "Itraconazole nanosuspension as aerosol foam formulation" for the treatment of skin diseases such as Cellulitis, Erysipelas, Impeigo and Blastomycosis, Histoplasmosis, Onchomycosis, etc. The solubility of poorly soluble itraconazole can be improved through nanosuspension process and also the absorption rate and bioavailability of drug can be enhanced by means of aerosol foam dispersion at the site of application.

Keywords


Itraconazole, Nanosuspension, Wet Milling, Foam.