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Kaur, A.
- An Echocardiographic Study in Patients with Non Haemorrhagic Cerebral Infarction to Find Cardiac Abnormalities
Authors
1 Medicine Unit 4 Guru Nanak Dev Hospital Govt. Medical College Amritsar, Punjab, IN
Source
International Journal of Medical and Dental Sciences, Vol 5, No 2 (2016), Pagination: 1171-1177Abstract
Background:Strokes are a major cause of morbidity and mortality worldwide. Majority are due to ischemic cerebral infarction. Ischemia may result from occlusion of blood vessels due to a disease process intrinsic to carotid and intracranial vessels or may relate to coexisting heart diseases, predisposing to embolic phenomenon.Objective: Echocardiographic study in patients with cerebrovascular accident, confirmed to be of non hemorrhagic nature on CT scan/MRI, for evidence of potential cardiac abnormalities as a predisposing cause for the vascular event.
Material and Methods: An observational study was conducted in department of medicine, GNDH, Amritsar. 50 patients of ischemic stroke were taken and 2D transthoracic echocardiography was done to find potential cardioembolic abnormalities.
Results: 76% of patients had echocardiographic abnormalities and 42% had potential cardioembolic abnormalities, out of which most common were ventricular wall hypokinesia, calcific aortic valve, rheumatic heart disease and dilated cardiomyopathy. The prevalence was almost similar in different age groups and both the sexes.
Conclusion: Prevalence of potential cardioembolic abnormalities is high (42%) in ischemic stroke patients and 2D echocardiography is therefore recommended in the management and secondary prevention of cardioembolic stroke, which has a higher mortality and more chances of recurrence than atherothrombotic type of ischemic stroke.
Keywords
Stroke, Echocardiography, Potential Cardioembolic Abnormalities, Cardioembolic Stroke.References
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- Relationship of Chronic Periodontitis and Plasma C-Reactive Protein during Pregnancy
Authors
1 Department of Periodontology and Oral Implantology, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, Punjab, IN
2 Guru Nanak Dev Hospital Amritsar, Punjab, IN
Source
International Journal of Medical and Dental Sciences, Vol 5, No 2 (2016), Pagination: 1208-1213Abstract
Background:Maternal periodontal disease is a chronic oral infection with local and systemic inflammatory responses and may be associated with adverse pregnancy outcomes. Elevated levels of Creactive protein has been linked to adverse pregnancy outcomes in maternal periodontal disease.Objectives: To assess plasma C-reactive protein levels in pregnant women with chronic periodontitis and in periodontal health and to compare the incidence of preterm delivery in pregnant women having chronic periodontitis and in periodontal health.
Materials and Methods: A total of 122 pregnant women aged 18 years and above with gestational age < 26 weeks were recruited and divided into two equal groups (control group, study group) of 61 each. Blood samples were taken from both the groups to determine the serum C-reactive protein.
Results: The mean value of C-reactive protein levels in subjects having chronic periodontitis was higher compared to control group i.e., 2.462±0.318 compared to 1.307±0.361 (P < 0.001). The incidence of preterm delivery (<37 weeks) was 82% in the chronic periodontitis group (study group) compared to 3.3% in the control group (P < 0.001). The incidence of low birth weight (<2500g) was 45.9% in chronic periodontitis (study group) compared to 14.8% in the control group (p < 0.001).
Conclusion: The findings from the study suggest that periodontal disease in pregnant women is associated with increased C-reactive protein levels in pregnancy. Incidence of preterm delivery and low birth weight infants is higher in pregnant women with chronic periodontitis compared to healthy controls.
Keywords
C-Reactive Protein, Preterm Birth, Low Birth Weight.References
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