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Emergence of Genome Wide Association Studies as a Major Plant Breeding Tool


Affiliations
1 Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur - 176 062, India
 

Identification of genes responsible for complex traits has been revolutionized with the advent and association of high throughput sequencing with association studies. GWAS takes the full advantage of ancient recombination events occurred in the natural population and exploits simple association of polymorphism with the trait of interest. Further, the genetic basis of phenotypic variations is detected by rapid highthroughput sequencing, accelerating the genome assisted breeding. The high density SNPs generated through GWAS allow whole genome scanning to identify haplotype blocks correlated with desired QTLs, thereby establishing itself as a major plant breeding tool.

Keywords

GWAS, Linkage Disequilibrium, SNPs.
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  • Emergence of Genome Wide Association Studies as a Major Plant Breeding Tool

Abstract Views: 180  |  PDF Views: 1

Authors

Neha Sharma
Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur - 176 062, India
R. K. Mittal
Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur - 176 062, India
V. K. Sood
Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur - 176 062, India
G. Katna
Department of Crop Improvement, CSK Himachal Pradesh Krishi Vishvavidyalaya, Palampur - 176 062, India

Abstract


Identification of genes responsible for complex traits has been revolutionized with the advent and association of high throughput sequencing with association studies. GWAS takes the full advantage of ancient recombination events occurred in the natural population and exploits simple association of polymorphism with the trait of interest. Further, the genetic basis of phenotypic variations is detected by rapid highthroughput sequencing, accelerating the genome assisted breeding. The high density SNPs generated through GWAS allow whole genome scanning to identify haplotype blocks correlated with desired QTLs, thereby establishing itself as a major plant breeding tool.

Keywords


GWAS, Linkage Disequilibrium, SNPs.

References