Refine your search
Collections
Co-Authors
Journals
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Kumar, Satish
- Neutral and Adaptive Genetic Variation in Indian Snow Leopards, Panthera uncia
Abstract Views :476 |
PDF Views:228
Authors
Affiliations
1 Oceanographic Research Institute, South African Association for Marine Biological Research, 1 King Shaka Avenue, Point, Durban 4001 KwaZulu-Natal, ZA
2 Institute for Integrated Natural Sciences, Zoology, University Koblenz-Landau, Koblenz, DE
3 Laboratory for Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Annexe I, Attapur Ring Road, Hyderabad 500 048, IN
4 CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, IN
5 Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201 002, IN
1 Oceanographic Research Institute, South African Association for Marine Biological Research, 1 King Shaka Avenue, Point, Durban 4001 KwaZulu-Natal, ZA
2 Institute for Integrated Natural Sciences, Zoology, University Koblenz-Landau, Koblenz, DE
3 Laboratory for Conservation of Endangered Species, CSIR-Centre for Cellular and Molecular Biology, Annexe I, Attapur Ring Road, Hyderabad 500 048, IN
4 CSIR-Centre for Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, IN
5 Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201 002, IN
Source
Current Science, Vol 125, No 2 (2023), Pagination: 204-209Abstract
In this study, we reveal patterns of genetic variation in snow leopards (Panthera uncia) by combining neutral (mtDNA, microsatellites) and adaptive (MHC II-DRB) genes. We collected 56 faecal samples from three locations in India. We observed moderate levels of microsatellite diversity (N = 32; A = 5.6; HO = 0.559). Nine unique MHC II-DRB sequences were identified in four snow leopard samples, of which 8 were novel. We found low levels of polymorphism in MHC class II-DRB exon, which was higher in captive (VA = 9.4%) compared to wild individuals (VA = 7.8%), likely as a result of a population bottleneckKeywords
Adaptive Evolution, Balancing Selection, Captive Breeding, Genetic Diversity, Major Histocompatibility Complex.References
- Frankham, R., Ballou, S. E. J. D., Briscoe, D. A. and Ballou, J. D., Introduction to Conservation Genetics, Cambridge University Press, Cambridge, 2002.
- Willoughby, J. R., Fernandez, N. B., Lamb, M. C., Ivy, J. A., Lacy, R. C. and DeWoody, J. A., The impacts of inbreeding, drift and selection on genetic diversity in captive breeding populations. Mol. Ecol., 2015, 24, 98–110.
- Hedrick, P. W., Conservation genetics: where are we now? Trends Ecol. Evol., 2001, 16, 629–636.
- Woodworth, L. M., Montgomery, M. E., Briscoe, D. A. and Frankham, R., Rapid genetic deterioration in captive populations: causes and conservation implications. Conserv. Genet., 2002, 3, 277-288.
- Frankham, R., Genetic adaptation to captivity in species conservation programs. Mol. Ecol., 2008, 17, 325–333.
- Zimmerman, S. J., Aldridge, C. L. and Oyler-McCance, S. J., An empirical comparison of population genetic analyses using micro-satellite and SNP data for a species of conservation concern. BMC Genomics, 2020, 21, 1–16.
- Janjua, S. et al., Improving our conservation genetic toolkit: ddRAD-seq for SNPs in snow leopards. Conserv. Genet. Resour., 2020, 12, 257–261.
- Klein, J., Natural History of the Major Histocompatibility Complex, Wiley, 1986.
- Hedrick, P. W. and Kim, T. J., Genetics of complex polymorphisms: parasites and maintenance of the major histocompatibility complex variation. In Evolutionary Genetics: From Molecules to Morphology (eds Singh, R. S. et al.), Cambridge University Press, Cambridge, 2000, pp. 204–234.
- Sachdev, M., Sankaranarayanan, R., Reddanna, P., Thangaraj, K. and Singh, L., Major histocompatibility complex class I polymorphism in Asiatic lions. Tissue Antigens, 2005, 66, 9–18.
- Marsden, C., Verberkmoes, H., Thomas, R., Wayne, R. and Mable, B., Pedigrees, MHC and microsatellites: an integrated approach for genetic management of captive African wild dogs (Lycaon pictus). Conserv. Genet., 2013, 14, 171–183.
- Li, X., Schuler, M. A. and Berenbaum, M. R., Molecular mechanisms of metabolic resistance to synthetic and natural xenobiotics. Annu. Rev. Entomol., 2007, 52, 231–253.
- Shrestha, B. and Kindlmann, P., Implications of landscape genetics and connectivity of snow leopard in the Nepalese Himalayas for its conservation. Sci. Rep., 2020, 10, 1–11.
- McCarthy, T., Mallon, D., Jackson, R., Zahler, P. and McCarthy, K., Panthera uncia. IUCN Red List Threat, Species, 2017, e-T22732A50664030.
- Bhatnagar, Y. V. et al., South Asia: India. In Snow leopards, Elsevier, Academic Press, Amsterdam, The Netherlands, 2016, pp. 457–469.
- Suryawanshi, K. et al., Estimating snow leopard and prey populations at large spatial scales. Ecol. Solut. Evid., 2021, 2, e12115.
- Janecka, J. E. et al., Range-wide snow leopard phylogeography supports three subspecies. J. Hered., 2017, 108, 597–607.
- Aruge, S., Batool, H., Khan, F. M. and Janjua, S., A pilot study – genetic diversity and population structure of snow leopards of Gilgit-Baltistan, Pakistan, using molecular techniques. Peer J., 2019, 7, e7672.
- Cho, Y. S. et al., The tiger genome and comparative analysis with lion and snow leopard genomes. Nat. Commun., 2013, 4, 2433.
- Singh, V. K., Singh, S. K., Joshi, B. D., Chandra, K., Sharma, L. K. and Thakur, M., Population genetics of the snow leopards (Panthera uncia) from the Western Himalayas, India. Mamm. Biol., 2022, 102, 263–269.
- Munson, L. and Worley, M., Veno-occlusive disease in snow leopards (Panthera uncia) from zoological parks. Vet. Pathol., 1991, 28, 37–45.
- Johnston, L., Armstrong, D. and Brown, J., Seasonal effects on seminal and endocrine traits in the captive snow leopard (Panthera uncia). Reproduction, 1994, 102, 229–236.
- Fitzpatrick, J. L. and Evans, J. P., Reduced heterozygosity impairs sperm quality in endangered mammals. Biol. Lett., 2009, 5, 320–323.
- Storfer, A., Gene flow and endangered species translocations: a topic revisited. Biol. Conserv., 1999, 87, 173–180.
- Parmar, D. R., Mitra, S., Bhadouriya, S., Rao, T., Kunteepuram, V. and Gaur, A., Characterization of major histocompatibility complex class I, and class II DRB loci of captive and wild Indian leopards (Panthera pardus fusca). Genetica, 2017, 145, 541–558.
- Wei, K. et al., Lineage pattern, trans-species polymorphism, and selection pressure among the major lineages of feline Mhc-DRB peptide-binding region. Immunogenetics, 2010, 62, 307–317.
- Riordan, P., Cushman, S. A., Mallon, D., Shi, K. and Hughes, J., Predicting global population connectivity and targeting conservation action for snow leopard across its range. Ecography, 2016, 39, 419-426.
- Pokorny, I., Sharma, R., Goyal, S. P., Mishra, S. and Tiedemann, R., MHC class I and MHC class II DRB gene variability in wild and captive Bengal tigers (Panthera tigris tigris). Immunogenetics, 2010, 62, 667–679.
- Uphyrkina, O. et al., Phylogenetics, genome diversity and origin of modern leopard, Panthera pardus. Mol. Ecol., 2001, 10, 2617–2633.
- Charruau, P. et al., Phylogeography, genetic structure and population divergence time of cheetahs in Africa and Asia: evidence for long-term geographic isolates. Mol. Ecol., 2011, 20, 706–724.
- Yuhki, N. and O’Brien, S. J., Nature and origin of polymorphism in feline MHC class II DRA and DRB genes. J. Immunol., 1997, 158, 2822–2833.
- Zecherle, L. J. et al., Subspecies hybridization as a potential conservation tool in species reintroductions. Evol. Appl., 2021, 14, 1216– 1224.
- Yuhki, N. and O’Brien, S. J., Nature and origin of polymorphism in feline MHC class II DRA and DRB genes. J. Immunol., 1997, 158, 2822–2833.
- Kaufman, J., Salomonsen, J. and Flajnik, M., Evolutionary conservation of MHC class I and class II molecules – different yet the same. Semin. Immunol., 1994, 6, 411–424.
- Zhang, F., Jiang, Z., Zeng, Y. and McCarthy, T., Development of primers to characterize the mitochondrial control region of snow leopard (Uncia uncia). In Genbank Submittion, Institute of Zoology, Chinese Academy of Science, Beijing, 2007.
- A comparative study of various dressings and their efficacy in second-degree superficial burns
Abstract Views :262 |
Authors
Affiliations
1 Plastic and Reconstructive Surgery Department, SRM Medical College Hospital and Research Centre, Chennai 603 203, IN
1 Plastic and Reconstructive Surgery Department, SRM Medical College Hospital and Research Centre, Chennai 603 203, IN
Source
Current Science, Vol 127, No 12 (2024), Pagination: 1434-1439Abstract
Second-degree superficial burns are prevalent, with scalds in extremities being the most frequent cause. They are treated initially with dressings such as wet collagen and nanocrystalline silver, and they mostly heal by conservative means, rarely requiring skin grafts. Here we aim to compare the efficacy of nanocrystalline silver and collagen dressings for second-degree superficial burns and to establish a standard protocol for managing such burns. It indicates that nanocrystalline silver dressings are more effective than collagen dressings in promoting faster epithelialization of second-degree burns and are associated with lower pain levels during treatment. However, there is no significant difference between the two groups regarding the need for split skin thickness grafts.Keywords
Collagen, epithelialization, nanocrystalline silver, scalds, superficial burns.Full Text
