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Current Science

Year

2017

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Hobbs, Samuel

Role of Inflammation in Diabetic Retinopathy:Therapeutic Targets

Abstract Views :289 | PDF Views:66

Authors

Samuel Hobbs ¹, Finny Monickaraj ¹, Paul McGuire ², Arup Das ¹

Affiliations
1 Department of Surgery/Ophthalmology, University of New Mexico School of Medicine, MSC 10 8000, 1600 University Blvd. NE, Albuquerque, NM 87131, US
2 Department of Cell Biology and Physiology, University of New Mexico School of Medicine, MSC 10 8000, 1600 University Blvd. NE, Albuquerque, NM 87131, US

Source

Current Science, Vol 113, No 07 (2017), Pagination: 1287-1295

Abstract

Inflammation plays a key role in the pathogenesis of diabetic retinopathy (DR), leading to alterations in the blood–retinal barrier and increased vascular permeability. Many anti-VEGF medications are now available for the treatment of DR, but response to these medications is not as robust in patients with diabetic macular oedema. Newer biologic agents are currently under study to improve the treatment of DR. These have shown promising results to both decrease the treatment burden of intravitreal injections and improve visual outcomes for diabetic patients.

Keywords

Chemokines, Cytokines, Diabetic Retinopathy, Drug Therapy, Inflammation.

Full Text

References

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