Refine your search
Collections
Co-Authors
Journals
Year
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Nandi, S. K.
- Bioactive Metabolite Profiling for Identification of Elite Germplasms:A Conservation Strategy for Threatened Medicinal Plants
Abstract Views :272 |
PDF Views:73
Authors
Affiliations
1 TransDisciplinary University, Foundation for Revitalisation of Local Health Traditions, 74/2, Jarakabhande Kaval, Attur Post, via Yelahanka, Bengaluru 560 106, IN
2 G.B. Pant National Institute of Himalayan Environment and Sustainable Development, Kosi-Katarmal, Almora 263 643, IN
1 TransDisciplinary University, Foundation for Revitalisation of Local Health Traditions, 74/2, Jarakabhande Kaval, Attur Post, via Yelahanka, Bengaluru 560 106, IN
2 G.B. Pant National Institute of Himalayan Environment and Sustainable Development, Kosi-Katarmal, Almora 263 643, IN
Source
Current Science, Vol 114, No 03 (2018), Pagination: 554-561Abstract
Medicinal plants are used as a source of raw drugs, chemical compounds or bioactive metabolites. Many of the medicinal plant species are facing threat of extinction due to indiscriminate harvesting by humans. Conservation of such species is no longer an altruistic choice but a necessity to ensure sustainable supply of bioactive compounds to the drug industry. This article demonstrates that conservation of threatened species is possible through large-scale cultivation of elite germplasm identified using biochemical markers. Six species, viz. Aconitum balfourii Stapf, Aconitum heterophyllum Wall. ex Royle, Podophyllum hexandrum Royle (syn = Sinopodophyllum hexandrum (Royle) T. S. Ying), Picrorhiza kurroa Royle ex Berth., Berberis aristata DC. and Embelia ribes Burm. f. were selected for the study under the all-India coordinated project on threatened species. The approach proved to be effective for bringing back the species from the verge of extinction.Keywords
Bioactive Metabolites, Conservation Strategy, Medicinal Plants, Elite Germplasm.References
- Collin, H. A., Secondary metabolite formulations in plant tissue cultures. Plant Growth Regul., 2001, 34, 119–134.
- Sarup, P., Bala, S. and Kamboj, S., Pharmacology and phytochemistry of oleo-gum resin of Commiphora wightii (Guggulu). Scientifica, 2015, 2015, 138039.
- Nadeem, M., Palni, L. M. S., Kumar, A. and Nandi, S. K., Podophyllotoxin content, above- and below-ground biomass in relation to altitude in Podophyllum hexandrum populations from Kumaun region of the Indian central Himalaya. Planta Med., 2007, 73, 388–391.
- Pandey, H., Nandi, S. K., Kumar, A., Agnihotri, R. K. and Palni, L. M. S., Aconitine alkaloids from tubers of Aconitum heterophyllum and A. balfourii: critically endangered medicinal herbs of Indian Central Himalaya. Natl. Acad. Sci. Lett., 2008, 31, 89–93.
- Pandey, H., Nandi, S. K. and Palni, L. M. S., Podophyllotoxin content in leaves and stem of Podophyllum hexandrum Royle from Indian Himalayan region. J. Med. Plants Res., 2013, 7, 3237–3241.
- Pandey, H., Kumar, A., Palni, L. M. S. and Nandi, S. K., Podophyllotoxin content in rhizome and ischolar_main samples of Podophyllum hexandrum Royle populations from Indian Himalayan region. J. Med. Plants Res., 2015, 9, 320–325.
- Naik, P. K., Alam, M. A., Singh, H., Goyal, V., Parida, S., Kalia, S. and Mohapatra, T., Assessment of genetic diversity through RAPD, ISSR and AFLP markers in Podophyllum hexandrum: a medicinal herb from the north-western Himalayan region. Physiol. Mol. Biol. Plant, 2010, 16, 135–148.
- Tiwari, S. S., Pandey, M. M., Srivastava, S. and Rawat, A. K. S., TLC densitometric quantifiation of picrosides (picroside-I and picrosideII) in Picrorhiza kurrooa and its substitute Picrorhiza scrophulariiflra and their antioxidant studies. Biomed. Chromatogr., 2012, 26, 61–68.
- Kuruvilla, G. R., Neeraja, M., Srikrishna, A., Rao, G. S. R. S., Sudhakar, A. V. S. and Venkatasubramanian, P., A new quinone from Maesa indica (Roxb.) A.DC, (Myrsinaceae). Indian J. Chem., 2010, 49B, 1637–1641.
- Venkatasubramanian, P., Kumar, S. K. and Nair, V. S., Cyperus rotundus, a substitute for Aconitum heterophyllum: studies on the ayurvedic concept of Abhava Pratinidhi Dravya (drug substitution). J. Ayurveda Integr. Med., 2010, 1(1), 33–39.
- Ajikumar, P. K., Tyo, K., Carlsen, S., Mucha, O., Phon, T. H. and Stephanopoulos, G., Terpenoids: opportunities for biosynthesis of natural product drugs using engineered microorganisms. Mol. Pharm., 2008, 5(2), 167–190.
- Sacchettini, J. C. and Poulter, C. D., Creating isoprenoid diversity. Science, 1997, 277, 1788–1789.
- Grassmann, J., Terpenoids as plant antioxidants. Vit. Horm., 2005, 72, 505–535.
- Irchhaiya, R. et al., Metabolites in plants and its classification. World J. Pharm. Pharm. Sci., 2015, 4(1), 287–305.
- Lu, J. J., Bao, J. L., Chen, X. P., Huang, M. and Wang, Y. T., Alkaloids isolated from natural herbs as the anticancer agents. Evid. Based Complement. Alter. Med., 2012, 2012, 485042.
- Cordell, G. A., Introduction to Alkaloids. A Biogenetic Approach, Wiley-Interscience, New York, USA, 1981.
- Hesse, M., Alkaloids – Nature’s Curse or Blessing, Wiley-VCH, Weinheim, 2002.
- Buckingham, J., Baggaley, K. H., Roberts, A. D. and Szabo L. F., Dictionary of Alkaloids, CRC Press, Florida, USA, 2010.
- Cheynier, V., Comte, G., Davies, K. M., Lattanzio, V. and Martens, S., Plant phenolics: recent advances on their biosynthesis, genetics, and ecophysiology. Plant Physiol. Biochem., 2013, 72, 1–20.
- Pandey, K. B. and Rizvi, S. I., Plant polyphenols as dietary antioxidants in human health and disease. Oxid. Med. Cell Longev., 2009, 2(5), 270–278.
- Croteau, R., Kutchan, T. M. and Lewis, N. G., Biochemistry and Molecular Biology of Plants, John Wiley and Sons, Oxford, UK, 2000.
- Buckingham, J. and Munasinghe, V. R. N., Dictionary of Flavonoids, CRC Press, Florida, USA, 2015.
- Yao, L. H., Jiang, Y. M., Shi, J., Tomás-Barberán, F. A., Datta, N., Singanusong, R. and Chen, S. S., Flavonoids in food and their health benefits. Plant Foods Hum. Nutr., 2004, 59(3), 113–122.
- Vetter, J., Plant cyanogenic glycosides. Toxicon, 2000, 38(1), 11–36.
- Sultankhodzhaev, M. N. and Nishnov, A. A., Proposed biogenesis of diterpenoid alkaloid. Chem. Nat. Prod., 1995, 31, 283–298.
- Srivastava, N., Sharma, V., Kamal, B. and Jadon, S., Aconitum: need for sustainable exploitation (with special reference to Uttarakhand). Int. J. Green Pharm., 2010, 4(4), 220–228.
- Nagarajan, M., Kuruvilla, G. R., Kumar, K. S. and Venkatasubramanian, P., Pharmacology of Ativisha, Musta and their substitutes. J. Ayurveda Integr. Med., 2015, 6(2), 121–133.
- Canel, C., Moraes, R. M., Dyan, F. E. and Ferreira, D., Molecules of interest: podophyllotoxin. Phytochemistry, 2000, 54, 115–120.
- Schacter, L., Etoposide phosphate: what, why, where and how? Sem. Oncol., 1996, 23, 1–7.
- Van Uden, W., Pras, N., Visser, J. F. and Malingre, T. M., Detection and identification of podophyllotoxin produced by cell cultures derived from Podophyllum hexandrum Royle. Plant Cell Rep., 1989, 8, 165–168.
- Fay, D. A. and Ziegler, W., Botanical source differentiation of Podophyllum resin by high performance liquid chromatography. J. Liq. Chromatogr., 1985, 8, 1501–1506.
- Anon., The Ayurvedic Pharmacopoeia of India, Part I, Vol. II, Government of India, Ministry of Health and Family Welfare, Department of Indian Systems of Medicine & Homoeopathy, 1999.
- Sack, R. B. and Froehlich, J. L., Berberine inhibits intestinal secretory response of Vibrio cholerae and Escherichia coli enterotoxins. Infect. Immunol., 1982, 35(2), 471–475.
- Kirtikar, K. R. and Basu, B. D., Indian Medicinal Plants, International Book Publications, Dehradun, 1995.
- Ved, D. K. and Goraya G. S., Demand and Supply of Medicinal Plants, Foundation for Revitalization of Local Health Traditions, Bangalore, 2008.
- Saied, S., Batool, S. and Naz, S., Phytochemical studies of Berberis aristata. J. Basic Appl. Sci., 2007, 3(1), 1–4.
- Wongbutdee, J., Physiological effects of berberine. Thai Pharm. Health Sci. J., 2009, 4, 78–83.
- Affuso, F., Ruvolo, A., Micillo, F., Saccà, L. and Fazio, S., Effects of a nutraceutical combination (berberine, red yeast rice and policosanols) on lipid levels and endothelial function randomized, double-blind, placebo-controlled study. Nutr. Metab. Cardiovasc. Dis., 2010, 20(9), 656–661.
- Mhaskar, M., Joshi, S., Chavan, B., Joglekar, A., Barve, N. and Patwardhan, A., Status of Embelia ribes Burm f. (Vidanga), an important medicinal species of commerce from northern Western Ghats of India. Curr. Sci., 2011, 100(4), 547–525.
- Souravi, K. and Rajasekharan, P. E., A review on the pharmacology of Embelia ribes Burm. F. – a threatened medicinal plant. Int. J. Pharm. Biol. Sci., 2014, 5(2), 443–456.
- Purohit, A. N., Lata, H., Nautiyal, S and Purohit, M. C., Some characteristics of four morphological variants of Podophyllum hexandrum Royle. Plant Genet. Res. Newsl., 1998, 114, 51–52.
- Sharma, T. R., Singh, B. M., Sharma, N. R. and Chauhan, R. S., Identification of high podophyllotoxin producing biotypes of Podophyllum hexandrum Royle from North-Western Himalaya. J. Plant Biochem. Biotechnol., 2000, 9, 49–51.
- Kitchlu, S., Ram, G., Koul, S., Koul, K., Gupta, K. K. and Ahuja, A., Podophyllum lignans array of Podophyllum hexandrum Royle population from semi-desert alpine region of Zanskar valley in Himalayas. Ind. Crops Prod., 2011, 33, 584–587.
- Pandey, H., Nandi, S. K., Kumar, A., Palni, U. T. and Palni, L. M. S., Podophyllotoxin content in Podophyllum hexandrum Royle plants of known age of seed origin and grown at a lower altitude. Acta. Physiol. Plant, 2007, 29, 121–126.
- Bastos, J. K., Burandt, Jr, Nanayakkara, L. and Bryanat Mechesney, J. D., Quantification of aryltetralin lignans in plants parts and among different populations of Podophyllum peltatum by reverse phase high performance liquid chromatography. J. Nat. Prod., 1996, 59, 406–408.
- Moraes, R. M., Momm, H. G., Silva, B., Maddox, V., Easson, G. L., Lata, H. and Ferreira, D., Geographic information system method for assessing chemo-diversity in medicinal plants. Planta Med., 2005, 71, 1157–1164.
- Purohit, H., Nautiyal, B. P. and Nautiyal, M. C., Interpopulation variation in Picrorhiza kurrooa Royle ex Benth – step towards identifying genetic variability and elite strains for crop improvement study. Am. J. Plant Physiol., 2008, 3, 154–164.
- Sharma, N., Pathania, V., Singh, B. and Gupta, R. C., Intraspecific variability of main phytochemical compounds in Picrorhiza kurrooa Royle ex Benth. from north Indian higher altitude Himalayas using reverse-phase high performance liquid chromatography. J. Med. Plants Res., 2012, 6, 3181–3187.
- Sarin, Y. K., Illustrated Manual of Herbal Drugs used in Ayurveda (CSIR/ICMR), NISCOM, New Delhi, 1996.
- Anon., The Ayurvedic Formulary of India, Part I, Government of India, Ministry of Health and Family Welfare, Department of Indian Systems of Medicine and Homoeopathy, New Delhi, 2003.
- Choudhury, R. P., Md. Ibrahim, A. and Bharathi, Padma, V., Quantitative analysis of embelin in Myrsine africana L. (Myrsinaceae) using HPLC and HPTLC. E-J. Food Plants Chem., 2007, 2, 20–24.
- Fowler, M. W., Problems in commercial exploitation of plant tissue cultures. In Primary and Secondary Metabolism of Plant Cell Cultures (eds Neumann, K. H., Barz, W. and Reinhardt, E.), Springer Verlag, Berlin, Germany, 1985, pp. 362–378.
- Hussain, M. S., Fareed, S., Ansari, S., Rahman, M. A., Ahmad, I. Z. and Saeed, M., Current approaches toward production of secondary plant metabolites. J. Pharm. Bioallied Sci., 2012, 4(1), 10–20.
- Caruso, M. et al., Studies on a strain of Kitasatospora sp. paclitaxel producer. Ann. Microbiol., 2000, 50(2), 89–102.
- Golinska, P., Wypij, M., Agarkar, G., Rathod, D., Dahm, H. and Rai, M., Endophytic actinobacteria of medicinal plants: diversity and bioactivity. Antonie Van Leeuwenhoek, 2015, 108(2), 267–289.
- Moraes, R. M., Burandt, C. L., Ganzera, M., Li, X., Khan, I. A. and Canel, C., The American May apple revisited – Podophyllum peltatum – still a potential cash crop? Econ. Bot., 2000, 54, 471–476.
- Moraes, R. M., Bedir, E., Burandt, C., Canel, C. and Khan, I. A., Evaluation of Podophyllum peltatum accessions for podophyllotoxin production. Planta Med., 2002, 68, 341–344.
- Zheljazkov, V. D., Cantrell, C. L. and Astatkie, T., Variation in podophyllotoxin concentration in leaves and rhizomes of American mayapple (Podophyllum peltatum L.). Ind. Crops Prod., 2011, 33, 633–637.
- In vitro Propagation of Some Threatened Plant Species of India
Abstract Views :237 |
PDF Views:99
Authors
C. R. Deb
1,
G. R. Rout
2,
A. A. Mao
3,
S. K. Nandi
4,
R. K. Nilasana Singha
3,
D. Vijayan
3,
T. Langhu
1,
Z. P. Kikon
1,
S. Pradhan
3,
Mohd Tariq
4,
D. Swain
2
Affiliations
1 Department of Botany, Nagaland University, Lumami 798 627, IN
2 Department of Agricultural Biotechnology, College of Agriculture, Orissa University of Agriculture and Technology, Bhubaneswar 751 003, IN
3 Botanical Survey of India, Eastern Regional Centre, Shillong 793 003, IN
4 G.B. Pant Institute of Himalayan Environment and Development, Kosi-Katarmal, Almora 263 643, IN
1 Department of Botany, Nagaland University, Lumami 798 627, IN
2 Department of Agricultural Biotechnology, College of Agriculture, Orissa University of Agriculture and Technology, Bhubaneswar 751 003, IN
3 Botanical Survey of India, Eastern Regional Centre, Shillong 793 003, IN
4 G.B. Pant Institute of Himalayan Environment and Development, Kosi-Katarmal, Almora 263 643, IN
Source
Current Science, Vol 114, No 03 (2018), Pagination: 567-575Abstract
To prevent extinction of threatened species, in vitro regeneration protocols for the propagation of six threatened species were standardized. The regenerated micro-shoots were ischolar_mained in nutrient medium supplemented with low concentrations of auxin. The well-developed plantlets were successfully established in field conditions, thus improving the probability of self-sustenance of the introduced populations. The success story of these six threatened species reaffirms the role of in vitro propagation in conserving plants facing the threat of extinction.Keywords
Conservation, In vitro Regeneration, Microshoots, Threatened Species.References
- MoEF, India’s 5th National report to the conservation on biological diversity. Ministry of Environment and Forest, Government of India, 2015, p. 142.
- Cruz-Cruz, C. A., Gonzalez-Arnao, M. A. and Engelmann, F., Biotechnology and conservation of plant biodiversity. Resources, 2013, 2, 73–95.
- Langhu, T. and Deb. C. R., Studies on the reproductive biology and seed biology of Aconitum nagarum Stapf: a threatened medicinal plant of North East India. J. Res. Biol., 2014, 4(7), 1465–1474.
- Engelmann, F., Germplasm collection, storage and conservation. In Plant Biotechnology and Agriculture (eds Altman, A. and Hasegawa, P. M.), Academic Press, Oxford, UK, 2012, pp. 255–268.
- Withers, L. A., Collecting in vitro for genetic resources conservation. In Collecting Plant Genetic Diversity (eds. Guarino, L., Rao, R. and Reid, R.), Centre for Agricultural Bioscience International, Wallingford, UK, 1995, pp. 511–515.
- Engelmann, F., Use of biotechnologies for the conservation of plant biodiversity. In Vitro Cell. Dev. Biol.–Plant, 2011, 47, 5–16.
- Arenmongla, T. and Deb, C. R., Studies on in vitro morphogenetic potential of nodal segments of Malaxis acuminate D. Don. Appl. Biol. Res., 2012, 14(2), 156–163.
- Deb, C. R. and Arenmongla, T., An efficient in vitro regeneration protocol for a natural dye yielding plant, Strobilanthes flaccidifolious Nees. from nodal explants. Indian J. Exp. Biol., 2012, 50, 810–816.
- Deb, M. S., Jamir, N. S. and Deb, C. R., In vitro culture of immature embryos of Cinnamomum tamala Nees. – the role of different factors. Indian J. Exp. Biol., 2014, 52, 1003–2010.
- Tandon, P. and Kumaria, S., Prospects of plant conservation biotechnology in India with special reference to north-eastern region. In Biodiversity: Status and Prospects (eds Tandon, P. and Kumaria, S.), Narosa Publishing House, New Delhi, 2005, pp. 79–91.
- Sharma, B. D. and Sanjappa, M., Flora of India, Botanical Survey of India, Kolkata, India, 1993, vol. 3, pp. 142–145.
- Samant, S. S., Diversity, nativity and endemism of vascular plants in a part of Nanda Devi Biosphere Reserve in West Himalaya I. Himalaya Biosphere Reserve (Biannual Bull.), 1999, 1(1–2), 1–28.
- Ernst, E., St John’s wort, an anti-depressant? a systematic, criteriabased review. Phytomedicine, 1995, 2, 67–71.
- Swain, D., Lenka, S., Hota, T. and Rout, G. R., Micro-propagation of Hypericum gaitii Haines, an endangered medicinal plants: assessment of genetic fidelity. Nucleus, 2016, 59(1), 7–13.
- Ved, D. K., Kinhal, G. A., Ravikumar, K., Prabhakaran, V., Ghate, U., Vijaya Sankar, R. and Indresha, J. H., Conservation assessment and management prioritization for the medicinal plants of Himachal Pradesh, Jammu & Kashmir and Uttaranchal. Foundation of Revitalization of Local Health Traditions, Bengaluru, 2003, pp. 1–24.
- Van Uden, W., Pras, N., Visser, J. F. and Malingre, T. M., Detection and identification of podophyllotoxin produced by cell cultures derived from Podophyllum hexandrum Royle. Plant Cell Rep., 1989, 8, 165–168.
- Canel, C., Moraes, R. M., Dyan, F. E. and Ferreira, D., Molecules of interest: podophyllotoxin. Photochemistry, 2000, 54, 115–120.
- Nadeem, M., Palni, L. M. S., Purohit, A. N., Pandey, H. and Nandi, S. K., Propagation and conservation of Podophyllum hexandrum Royle: an important medicinal herb. Biol. Conserv., 2000, 92, 121–129.
- Deb, C. R. and Imchen, T., An efficient in vitro hardening technique of tissue culture raised plants. Biotechnology, 2010, 9(1), 79–83.
- Mao, A. A. and Gogoi, R., Rhododendrons of Manipur and Nagaland, India. NeBIO, 2012, 3(1), 1–10.
- Wu, F. Q., Shen, S. K., Zhang, X. J., Wang, Y. H. and Sun, W. B., Genetic diversity and population structure of an extremely endangered species: the world’s largest Rhododendron. AoB PLANTS, 2015, 7, plu082; doi:10.1093/aobpla/plu082.
- Santos, A., Fidalgo, F., Santos, I. and Salema, R., In vitro bulb formation of Narcissus asturiensis, a threatened species of the Amaryllidaceae. J. Hortic. Sci. Biotechnol., 2002, 77, 149–152.
- Kyte, L. and Briggs, B., A simplified entry into tissue culture production of rhododendrons. Proc. Int. Plant Propaga. Soc., 1979, 29, 90–95.
- McCown, B. H. and Lloyd, C. B., A survey of the response of Rhododendron to in vitro culture. Plant Cell Tissue Organ Cult., 1982, 2, 77–85.
- De, A. and Hajra, P. K., Vanda in India. J. Orchid Soc. India, 2004, 18, 28–29.
- Karuppusamy, S., Aruna, V., Kiranmai, C. and Pullaiah, T., In vitro propagation of an endemic umbellifer, Hydrocotyle conferta. Indian J. Biotechnol., 2007, 6, 541–544.
- Dhavala, A. and Rathore, T. S., Micropropagation of Embelia ribes Burm f. through proliferation of adult axillary shoots. In Vitro Cell. Dev. Biol.–Plant., 2010, 46, 180–191.
- Mangal, M., Sharma, D., Sharma, M., Kher, R. and Singh, A. K., In vitro plantlet regeneration in Guava from nodal segments. Phytomorphology, 2008, 58, 103–108.
- Abhyankar, G. and Reddy, V. D., Rapid micropropagation via axillary bud proliferation of Adhatoda vasica Nees from nodal segments. Indian J. Exp. Biol., 2007, 45, 268–271.
- Liu, Z. R. and Sandford, J. C., Plant regeneration by organogenesis from strawberry leaf and runner tissue. Hortic. Sci., 1988, 23, 1057–1059.
- Rout, G. R., Mahato, A. and Senapati, S. K., In vitro clonal propagation of Nyctanthes arbortristis. Biol. Plant., 2008, 52, 521–524.
- Rout, G. R., Direct plant regeneration from leaf explants of Plumbago species and its genetic fidelity through RAPD markers. Ann. Appl. Biol., 2003, 140, 305–313.
- Calvo, M. C. and Segura, J., Plant regulation from cultured leaves of Lavandula latifolia Medicus: Influences of growth regulators and illumination condition. Plant Cell Tissue Organ Cult., 1989, 19, 33–42.
- Baraldi, R., Rossi, F. and Lercari, B., In vitro shoot development of Prunus GF 6652: interaction between light and benzyladenine. Plant Physiol., 1988, 74, 440–443.
- Cantos, M., Linan, J., Garcia, J. L., Linan, M. G., Dominguez, M. A. and Troncoso, A., The use of in vitro culture to improve the propagation of Rhododendron ponticum sub sp. baeticum (Boiss. & Reuter). Cent. Eur. J. Biol., 2007, 2, 297–306.
- Selvaraj, N., Vasudevan, A., Manickavasagam, M. and Ganapathi, A., In vitro organogenesis and plant formation in cucumber. Biol. Plant., 2006, 50, 123–126.
- Baskaran, P., Velayutham, P. and Jayabalan, N., In vitro regeneration of Melothriamadera spatana via indirect organogenesis. In Vitro Cell. Dev. Biol.–Plant., 2009, 45, 407–413.
- Manzanera, J. A. and Pardos, J. A., Micropropagation of juvenile and adult Quercus suber L. Plant Cell Tissue Organ Cult., 1990, 21, 1–8.