Current Science

Oshin John Miranda ¹, Ganga Srinivasan ¹

Affiliations
1 Vivekanand Education Society’s College of Pharmacy, Chembur, Mumbai 400 074, IN

Abstract

There are a wide variety of dressing techniques available for the management of both acute and chronic wounds. The primary objective in both the cases is to achieve a healed wound. An ideal dressing material should accelerate wound healing and reduce loss of necessary fluids from the wound, and also help minimize pain and infection. The present trend is to promote the concept of moist wound healing. This article emphasizes on the importance of assessment of the wound, the volume of drainage fluid, amount of damage, presence of infection and location of wound for optimal wound healing.

Keywords

Advanced Therapies, Controlled Drug Delivery Systems, Modern Dressings, Wound Healing.

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Bhagyashree Gurav ¹, Ganga Srinivasan ¹

Affiliations
1 Vivekanand Education Society College of Pharmacy, Hashu Advani Memorial Complex, Chembur East, Mumbai 400 074, IN

Abstract

Antisense oligonucleotides are novel, highly selective inhibitors or modulators of gene expression. Attention is now being paid for the use of these agents not only in the treatment of genetic disorders but also for nongenetic disorders, where the treatment involves modulation of gene expression. However, antisense oligonucleotides face immense challenges for their use as therapeutics and successful application of these agents requires appropriate design and delivery strategies to increase their stability and intracellular uptake.

Keywords

Antisense Oligonucleotides, Delivery Strategies, Gene Expression, Modulators, Therapeutics.

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