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Dagade, Dilip H.
- Analytical Estimation of Water Contents, Specific Heat Capacity and Thermal Profiles Associated with Enzymatic Model Compound β-Cyclodextrin
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Authors
Gaurav R. Gupta
1,
Pankaj D. Patil
1,
Vasim R. Shaikh
1,
Rahul R. Kolhapurkar
2,
Dilip H. Dagade
2,
Kesharsingh J. Patil
1
Affiliations
1 School of Chemical Sciences, North Maharashtra University, Jalgaon 425 001, IN
2 Department of Chemistry, Shivaji University, Kolhapur 416 004, IN
1 School of Chemical Sciences, North Maharashtra University, Jalgaon 425 001, IN
2 Department of Chemistry, Shivaji University, Kolhapur 416 004, IN
Source
Current Science, Vol 114, No 12 (2018), Pagination: 2525-2529Abstract
Studies of water contents of solid β-cyclodextrin (β-CD) in crystallized and vacuum dried conditions are reported. Water contents were estimated using Karl–Fischer (KF) titration and thermo-gravimetric analysis (TGA) techniques. It was found that the water contents for crystallized and vacuum-dried samples were 6.93 and 0.86 moles of water per β-CD molecule respectively. TGA studies gave values of 6.83 and 0.52 moles of water per β-CD molecule respectively. The results agree with those reported from X-ray diffraction studies. Also, the molecular weight of the vacuum dried sample was determined using vapour pressure osmometry, which agrees well with the actual molecular weight of β-CD. The thermal profiles of α-cyclodextrin (α-CD) and β-CD are presented. The differential scanning calorimetry data was used to calculate specific heat at constant pressure (Cp) at different temperatures (338.15–468.15 K). These results are compared with similar data for α-CD and discussed in terms of motional contribution to Cp values and related conformational effects.Keywords
Cyclodextrins, Differential Scanning Calorimetry, Specific Heat Capacity, Thermo-Gravimetric Analysis.Full Text
References
- Lehn, J. M., Toward self-organization and complex matter. Science, 2002, 295, 2400–2403.
- Patil, K., Pawar, R. and Dagade, D., Studies of osmotic and activity coefficients in aqueous and CCl4 solutions of 18-Crown-6 at 25°C. J. Phys. Chem. A, 2002, 106, 9606–9611.
- Dagade, D. H., Kolhapurkar, R. R., Terdale, S. S. and Patil, K. J., Thermodynamics of aqueous solutions of 18-Crown-6 at 298.15 K: enthalpy and entropy effects. J. Solution Chem., 2005, 34, 415–426.
- Terdale, S. S., Dagade, D. H. and Patil, K. J., Thermodynamic studies of molecular interactions in aqueous α-cyclodextrin solutions: application of McMillan-Mayer and Kirkwood-Buff theories. J. Phys. Chem. B, 2006, 110, 18583–18593.
- Terdale, S. S., Dagade, D. H. and Patil, K. J., Thermodynamic studies of drug-α-cyclodextrin interactions in water at 298.15 K: Promazine hydrochloride/chloropromazine hydrochloride + α-cyclodextrin + H2O systems. J. Phys. Chem. B, 2007, 111, 13645–13652.
- Terdale, S. S., Dagade, D. H. and Patil, K. J., Activity and activity coefficient studies of aqueous binary and ternary solutions of 4-nitrophenol, sodium salt of 4-nitrophenol, hydroquinone and α-cyclodextrin at 298.15 K. J. Mol. Liq., 2008, 139, 61–71.
- Shaikh, V. R., Terdale, S. S., Hundiwale, D. G. and Patil, K. J., Thermodynamic studies of drug-α-cyclodextrin interactions in water at 298.15 K: procaine hydrochloride/lidocaine hydrochloride/tetracaine hydrochloride + α-cyclodextrin + H2O systems. J. Chem. Thermodyn., 2014, 68, 161–168.
- Shaikh, V. R., Hundiwale, D. G. and Patil, K. J., A volumetric approach: Interactions of some local anesthetical drugs with α-cyclodextrin in aqueous solutions at 298.15 K. J. Chem. Thermodyn., 2017, 107, 51–57.
- Shaikh, V. R., Terdale, S. S., Abdul, A., Gupta, G. R., Hundiwale, D. G. and Patil, K. J., Volumetric studies of 2,2,2-cryptand in aqueous and aqueous KBr solutions at 298.15 K: an example involving solvent-induced hydrophilic and hydrophobic interactions. J. Solution Chem., 2013, 42, 2087–2103.
- Shaikh, V. R., Terdale, S. S., Abdul, A., Gupta, G. R., Hundiwale, D. G. and Patil, K. J., Thermodynamic studies of aqueous solutions of 2,2,2-cryptand at 298.15 K: Enthalpy−entropy compensation, partial entropies, and complexation with K+ ions. J. Phys. Chem. B, 2013, 117, 16249–16259.
- Manor, P. C. and Saenger, W., Topography of cyclodextrin inclusion complexes. III. Crystal and molecular structure of cyclohexaamylose hexahydrate, the water dimer inclusion complex. J. Am. Chem. Soc., 1974, 96, 3630–3639.
- Linder, K. and Saenger, W., β-Cyclodextrin dodecahydrate: Crowding of water molecules within a hydrophobic cavity. Angew. Chem. Int. Ed. Engl., 1978, 17, 694–695.
- Saenger, W., Cyclodextrin inclusion compounds in research and industry. Angew. Chem. Int. Ed. Engl., 1980, 19, 344–362.
- Saenger, W. et al., Structures of the common cyclodextrins and their larger analogues beyond the doughnut. Chem. Rev., 1998, 98, 1787–1802.
- Szejtli, J., Introduction and general overview of cyclodextrin chemistry. Chem. Rev., 1998, 98, 1743–1754.
- Emmerich, W. and Trevor, M. L., Heat capacities liquids, solutions and vapours. The Royal Society of Chemistry, 2010.
- Jolicoeur, C., Lemelin, L. L. and Lapalme, R., Heat capacity of potassium-crown ether complexes in aqueous solution. Manifestations and quantitative treatment of important relaxational heat capacity effects. J. Phys. Chem., 1979, 83, 2806–2808.
- Briggner, L. E. and Wadsö, I., Heat capacities of maltose, maltotriose, maltotetrose and -, -, and -cyclodextrin in the solid state and in dilute aqueous solution. J. Chem. Thermodyn., 1990, 22, 1067–1074.
- Haines, P. J., Thermal Methods of Analysis, Principles, Applications and Problems, Springer, The Netherlands, 1995.
- Burns, J. A. and Verrall, R. E., Thermodynamics of tetraalkyl- and bis-tetraalkylammonium bromides: II. Heat capacities of solid state from 273 to 373 K. Thermochim. Acta, 1974, 9, 277–288.
- Dortmund Data Bank; http://www.ddbst.com/en/EED/PCP/HCP_C4577.php
- Pelc, H. W., Hempelmann, R., Prager, M. and Zeidler, M. D. Dynamics of 18-Crown-6 ether in aqueous solution studied by quasielastic neutron scattering. Ber. Bunseiiges. Phys. Chem., 1991, 95, 2510–2516.
- Lehn, J. M., Cryptate inclusion complexes, effects on solute-solute and solute-solvent interactions and on ionic reactivity. Pure Appl. Chem., 1980, 52, 2303–2319.